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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM5
All Species:
20
Human Site:
S12
Identified Species:
33.85
UniProt:
P33992
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P33992
NP_006730.2
734
82286
S12
D
D
P
G
I
F
Y
S
D
S
F
G
G
D
A
Chimpanzee
Pan troglodytes
XP_001156025
734
82237
S12
D
D
P
G
I
F
Y
S
D
S
F
G
G
D
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_853134
634
70391
Cat
Felis silvestris
Mouse
Mus musculus
P49718
733
82324
S12
D
D
P
G
I
F
Y
S
D
S
F
G
G
D
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006243
734
82391
S12
D
E
P
G
I
Y
Y
S
D
S
F
G
V
D
T
Frog
Xenopus laevis
P55862
735
82417
D13
D
L
G
V
Y
Y
S
D
S
F
G
G
E
Q
Q
Zebra Danio
Brachydanio rerio
NP_848523
736
81753
D13
D
P
G
V
Y
Y
S
D
S
F
G
G
G
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q26454
866
96592
V153
S
S
Q
A
P
Q
L
V
V
W
G
T
N
V
V
Honey Bee
Apis mellifera
XP_624292
732
82413
S12
D
D
P
G
I
F
F
S
D
N
F
S
I
S
E
Nematode Worm
Caenorhab. elegans
Q21902
759
84917
Q12
D
N
P
G
I
Y
Y
Q
E
R
F
F
A
N
D
Sea Urchin
Strong. purpuratus
XP_801948
734
82932
S12
D
D
P
G
I
F
F
S
D
N
F
G
S
E
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9SX03
768
85190
K12
E
E
A
M
A
A
H
K
R
A
F
L
D
F
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43299
716
80315
A13
F
D
G
D
K
G
L
A
K
G
F
L
E
N
F
Baker's Yeast
Sacchar. cerevisiae
P29496
775
86392
D21
L
Q
G
E
S
P
N
D
D
D
N
T
E
I
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
N.A.
82.1
N.A.
94.8
N.A.
N.A.
N.A.
88.1
86.2
80.3
N.A.
28.6
69.8
59.9
74.9
Protein Similarity:
100
99.7
N.A.
84.3
N.A.
97.6
N.A.
N.A.
N.A.
95.6
96.1
92.2
N.A.
47.5
85.1
76.5
89.3
P-Site Identity:
100
100
N.A.
0
N.A.
93.3
N.A.
N.A.
N.A.
73.3
13.3
20
N.A.
0
60
40
66.6
P-Site Similarity:
100
100
N.A.
0
N.A.
93.3
N.A.
N.A.
N.A.
86.6
20
40
N.A.
0
73.3
66.6
86.6
Percent
Protein Identity:
N.A.
31.7
N.A.
31.6
47.2
N.A.
Protein Similarity:
N.A.
51.1
N.A.
50.1
62.8
N.A.
P-Site Identity:
N.A.
6.6
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
26.6
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
8
8
0
8
0
8
0
0
8
0
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
65
43
0
8
0
0
0
22
50
8
0
0
8
29
15
% D
% Glu:
8
15
0
8
0
0
0
0
8
0
0
0
22
15
8
% E
% Phe:
8
0
0
0
0
36
15
0
0
15
65
8
0
8
8
% F
% Gly:
0
0
29
50
0
8
0
0
0
8
22
50
29
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
50
0
0
0
0
0
0
0
8
8
8
% I
% Lys:
0
0
0
0
8
0
0
8
8
0
0
0
0
0
0
% K
% Leu:
8
8
0
0
0
0
15
0
0
0
0
15
0
0
8
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
8
0
0
15
8
0
8
15
0
% N
% Pro:
0
8
50
0
8
8
0
0
0
0
0
0
0
0
8
% P
% Gln:
0
8
8
0
0
8
0
8
0
0
0
0
0
8
8
% Q
% Arg:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% R
% Ser:
8
8
0
0
8
0
15
43
15
29
0
8
8
8
8
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
8
% T
% Val:
0
0
0
15
0
0
0
8
8
0
0
0
8
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
15
29
36
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _