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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM5
All Species:
43.94
Human Site:
S424
Identified Species:
74.36
UniProt:
P33992
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P33992
NP_006730.2
734
82286
S424
S
V
M
R
D
P
S
S
R
N
F
I
M
E
G
Chimpanzee
Pan troglodytes
XP_001156025
734
82237
S424
S
V
M
R
D
P
S
S
R
N
F
I
M
E
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_853134
634
70391
N379
A
G
I
T
T
T
L
N
S
R
C
S
V
L
A
Cat
Felis silvestris
Mouse
Mus musculus
P49718
733
82324
S423
S
V
I
R
D
P
S
S
R
N
F
I
M
E
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006243
734
82391
S424
S
V
I
R
D
P
S
S
R
S
F
F
M
E
G
Frog
Xenopus laevis
P55862
735
82417
S425
S
V
M
R
D
P
V
S
R
N
F
I
M
E
G
Zebra Danio
Brachydanio rerio
NP_848523
736
81753
T426
S
V
L
R
D
P
T
T
R
G
F
V
M
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q26454
866
96592
T555
Y
V
T
K
D
P
E
T
R
Q
L
V
L
Q
T
Honey Bee
Apis mellifera
XP_624292
732
82413
T421
S
V
L
R
D
P
I
T
R
N
F
V
M
E
G
Nematode Worm
Caenorhab. elegans
Q21902
759
84917
S423
S
V
I
R
D
P
Q
S
R
S
F
I
M
E
G
Sea Urchin
Strong. purpuratus
XP_801948
734
82932
T422
S
V
M
R
D
P
A
T
R
N
F
V
M
E
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9SX03
768
85190
N410
I
D
E
F
D
K
M
N
D
Q
D
R
V
A
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43299
716
80315
T419
A
V
M
R
D
Q
V
T
N
E
M
V
L
E
G
Baker's Yeast
Sacchar. cerevisiae
P29496
775
86392
T459
S
V
Q
R
D
P
M
T
R
E
F
Y
L
E
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
N.A.
82.1
N.A.
94.8
N.A.
N.A.
N.A.
88.1
86.2
80.3
N.A.
28.6
69.8
59.9
74.9
Protein Similarity:
100
99.7
N.A.
84.3
N.A.
97.6
N.A.
N.A.
N.A.
95.6
96.1
92.2
N.A.
47.5
85.1
76.5
89.3
P-Site Identity:
100
100
N.A.
0
N.A.
93.3
N.A.
N.A.
N.A.
80
93.3
66.6
N.A.
26.6
73.3
80
80
P-Site Similarity:
100
100
N.A.
26.6
N.A.
100
N.A.
N.A.
N.A.
93.3
93.3
93.3
N.A.
60
93.3
93.3
100
Percent
Protein Identity:
N.A.
31.7
N.A.
31.6
47.2
N.A.
Protein Similarity:
N.A.
51.1
N.A.
50.1
62.8
N.A.
P-Site Identity:
N.A.
6.6
N.A.
40
60
N.A.
P-Site Similarity:
N.A.
20
N.A.
66.6
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
0
0
0
0
8
0
0
0
0
0
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
8
0
0
93
0
0
0
8
0
8
0
0
0
0
% D
% Glu:
0
0
8
0
0
0
8
0
0
15
0
0
0
79
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
72
8
0
0
0
% F
% Gly:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
79
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
29
0
0
0
8
0
0
0
0
36
0
0
8
% I
% Lys:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
15
0
0
0
8
0
0
0
8
0
22
8
0
% L
% Met:
0
0
36
0
0
0
15
0
0
0
8
0
65
0
0
% M
% Asn:
0
0
0
0
0
0
0
15
8
43
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
79
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
8
8
0
0
15
0
0
0
8
0
% Q
% Arg:
0
0
0
79
0
0
0
0
79
8
0
8
0
0
0
% R
% Ser:
72
0
0
0
0
0
29
43
8
15
0
8
0
0
0
% S
% Thr:
0
0
8
8
8
8
8
43
0
0
0
0
0
0
8
% T
% Val:
0
86
0
0
0
0
15
0
0
0
0
36
15
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _