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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM5
All Species:
43.94
Human Site:
T609
Identified Species:
74.36
UniProt:
P33992
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P33992
NP_006730.2
734
82286
T609
R
R
S
S
I
P
I
T
V
R
Q
L
E
A
I
Chimpanzee
Pan troglodytes
XP_001156025
734
82237
T609
R
R
S
S
I
P
I
T
V
R
Q
L
E
A
I
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_853134
634
70391
L523
I
V
R
I
A
E
A
L
S
K
M
K
L
Q
P
Cat
Felis silvestris
Mouse
Mus musculus
P49718
733
82324
T608
R
R
S
S
I
P
I
T
V
R
Q
L
E
A
I
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006243
734
82391
T609
R
R
S
S
I
P
I
T
V
R
Q
L
E
A
I
Frog
Xenopus laevis
P55862
735
82417
T610
K
R
S
S
I
P
I
T
V
R
Q
L
E
A
I
Zebra Danio
Brachydanio rerio
NP_848523
736
81753
T611
R
R
V
S
I
P
I
T
V
R
Q
L
E
A
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q26454
866
96592
L739
Y
P
R
Q
L
E
S
L
I
R
L
S
E
A
H
Honey Bee
Apis mellifera
XP_624292
732
82413
T607
K
R
L
S
I
P
I
T
V
R
Q
L
E
A
I
Nematode Worm
Caenorhab. elegans
Q21902
759
84917
T633
H
N
S
A
I
P
I
T
V
R
Q
L
E
A
I
Sea Urchin
Strong. purpuratus
XP_801948
734
82932
T609
K
K
T
S
I
P
I
T
V
R
Q
L
E
A
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9SX03
768
85190
T605
G
G
G
T
L
P
I
T
A
R
T
L
E
T
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43299
716
80315
T598
N
T
P
H
S
Y
T
T
V
R
T
L
L
S
I
Baker's Yeast
Sacchar. cerevisiae
P29496
775
86392
T649
E
R
S
S
I
P
I
T
I
R
Q
L
E
A
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
N.A.
82.1
N.A.
94.8
N.A.
N.A.
N.A.
88.1
86.2
80.3
N.A.
28.6
69.8
59.9
74.9
Protein Similarity:
100
99.7
N.A.
84.3
N.A.
97.6
N.A.
N.A.
N.A.
95.6
96.1
92.2
N.A.
47.5
85.1
76.5
89.3
P-Site Identity:
100
100
N.A.
0
N.A.
100
N.A.
N.A.
N.A.
100
93.3
86.6
N.A.
20
86.6
80
80
P-Site Similarity:
100
100
N.A.
6.6
N.A.
100
N.A.
N.A.
N.A.
100
100
93.3
N.A.
33.3
93.3
86.6
100
Percent
Protein Identity:
N.A.
31.7
N.A.
31.6
47.2
N.A.
Protein Similarity:
N.A.
51.1
N.A.
50.1
62.8
N.A.
P-Site Identity:
N.A.
46.6
N.A.
33.3
86.6
N.A.
P-Site Similarity:
N.A.
60
N.A.
40
93.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
0
8
0
8
0
0
0
0
79
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
0
0
0
0
15
0
0
0
0
0
0
86
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
8
0
0
8
72
0
79
0
15
0
0
0
0
0
79
% I
% Lys:
22
8
0
0
0
0
0
0
0
8
0
8
0
0
0
% K
% Leu:
0
0
8
0
15
0
0
15
0
0
8
86
15
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
8
8
0
0
79
0
0
0
0
0
0
0
0
8
% P
% Gln:
0
0
0
8
0
0
0
0
0
0
72
0
0
8
0
% Q
% Arg:
36
58
15
0
0
0
0
0
0
93
0
0
0
0
0
% R
% Ser:
0
0
50
65
8
0
8
0
8
0
0
8
0
8
0
% S
% Thr:
0
8
8
8
0
0
8
86
0
0
15
0
0
8
0
% T
% Val:
0
8
8
0
0
0
0
0
72
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _