KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM7
All Species:
36.67
Human Site:
S143
Identified Species:
53.78
UniProt:
P33993
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P33993
NP_005907.3
719
81308
S143
L
Y
F
Q
G
P
S
S
N
K
P
R
V
I
R
Chimpanzee
Pan troglodytes
XP_527834
716
80774
S143
L
Y
F
Q
G
P
S
S
N
K
P
R
V
I
R
Rhesus Macaque
Macaca mulatta
XP_001101053
719
81187
S143
L
Y
F
Q
G
P
S
S
N
K
P
R
V
I
R
Dog
Lupus familis
XP_849809
719
81456
S143
L
Y
F
Q
G
P
S
S
N
K
P
R
V
I
R
Cat
Felis silvestris
Mouse
Mus musculus
Q61881
719
81192
S143
L
Y
F
R
G
P
S
S
S
K
P
R
V
I
R
Rat
Rattus norvegicus
NP_001004203
719
81044
S143
L
Y
F
Q
G
P
S
S
S
K
P
R
V
I
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZMN2
812
91233
H147
P
K
V
V
R
S
V
H
Y
C
P
A
T
K
K
Frog
Xenopus laevis
Q91876
720
81860
S142
L
Y
F
K
A
P
S
S
S
K
A
R
V
V
R
Zebra Danio
Brachydanio rerio
NP_997734
721
80978
T143
V
Y
F
R
P
P
A
T
L
K
P
R
V
V
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q26454
866
96592
A268
I
Q
V
R
P
F
N
A
D
K
T
R
N
M
R
Honey Bee
Apis mellifera
XP_393469
725
82814
T147
V
Y
F
K
D
F
D
T
T
K
A
Y
S
V
R
Nematode Worm
Caenorhab. elegans
NP_504199
730
81599
A156
V
Y
F
T
T
D
D
A
A
H
E
T
C
V
R
Sea Urchin
Strong. purpuratus
XP_780248
712
80030
K144
S
L
S
V
R
D
I
K
A
S
R
I
G
K
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9SX03
768
85190
D157
F
L
S
R
E
Y
R
D
I
T
S
F
V
G
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43299
716
80315
T142
P
S
K
G
R
P
S
T
I
R
E
V
K
A
S
Baker's Yeast
Sacchar. cerevisiae
P38132
845
94857
S221
R
Y
R
K
K
A
I
S
S
K
P
L
S
V
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.1
98.4
96.2
N.A.
92.7
94.3
N.A.
N.A.
32.6
83.7
80.5
N.A.
31.1
63.1
49.1
70.7
Protein Similarity:
100
96.6
99.3
98.1
N.A.
97.6
98.3
N.A.
N.A.
50.2
92.9
90
N.A.
48.6
77.6
68.9
84.7
P-Site Identity:
100
100
100
100
N.A.
86.6
93.3
N.A.
N.A.
6.6
66.6
53.3
N.A.
20
26.6
20
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
13.3
86.6
86.6
N.A.
60
53.3
40
0
Percent
Protein Identity:
N.A.
32
N.A.
50.3
42.2
N.A.
Protein Similarity:
N.A.
52.8
N.A.
67
58.9
N.A.
P-Site Identity:
N.A.
6.6
N.A.
13.3
33.3
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
26.6
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
7
7
13
13
0
13
7
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
7
0
0
7
0
0
% C
% Asp:
0
0
0
0
7
13
13
7
7
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
7
0
0
0
0
0
13
0
0
0
0
% E
% Phe:
7
0
63
0
0
13
0
0
0
0
0
7
0
0
0
% F
% Gly:
0
0
0
7
38
0
0
0
0
0
0
0
7
7
0
% G
% His:
0
0
0
0
0
0
0
7
0
7
0
0
0
0
0
% H
% Ile:
7
0
0
0
0
0
13
0
13
0
0
7
0
38
0
% I
% Lys:
0
7
7
19
7
0
0
7
0
69
0
0
7
13
7
% K
% Leu:
44
13
0
0
0
0
0
0
7
0
0
7
0
0
13
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% M
% Asn:
0
0
0
0
0
0
7
0
25
0
0
0
7
0
0
% N
% Pro:
13
0
0
0
13
57
0
0
0
0
57
0
0
0
0
% P
% Gln:
0
7
0
32
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
7
0
7
25
19
0
7
0
0
7
7
57
0
0
75
% R
% Ser:
7
7
13
0
0
7
50
50
25
7
7
0
13
0
7
% S
% Thr:
0
0
0
7
7
0
0
19
7
7
7
7
7
0
0
% T
% Val:
19
0
13
13
0
0
7
0
0
0
0
7
57
32
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
69
0
0
0
7
0
0
7
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _