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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM7
All Species:
27.88
Human Site:
S309
Identified Species:
40.89
UniProt:
P33993
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P33993
NP_005907.3
719
81308
S309
R
I
V
K
M
N
K
S
E
D
D
E
S
G
A
Chimpanzee
Pan troglodytes
XP_527834
716
80774
S309
R
I
V
K
M
N
K
S
E
D
D
E
S
G
A
Rhesus Macaque
Macaca mulatta
XP_001101053
719
81187
S309
R
I
V
K
M
N
K
S
E
D
D
E
S
G
A
Dog
Lupus familis
XP_849809
719
81456
S309
R
V
V
K
M
S
K
S
E
D
D
E
S
A
A
Cat
Felis silvestris
Mouse
Mus musculus
Q61881
719
81192
S309
W
I
V
K
M
T
K
S
D
D
D
V
S
G
A
Rat
Rattus norvegicus
NP_001004203
719
81044
S309
R
V
V
K
M
T
K
S
E
D
D
V
S
G
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZMN2
812
91233
F313
P
S
I
H
G
H
E
F
I
K
K
A
L
L
C
Frog
Xenopus laevis
Q91876
720
81860
S308
R
L
V
K
M
N
K
S
E
D
D
E
L
G
T
Zebra Danio
Brachydanio rerio
NP_997734
721
80978
T309
S
I
T
L
M
N
K
T
E
D
D
E
L
G
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q26454
866
96592
E434
V
D
N
K
R
L
Y
E
D
E
E
G
K
D
H
Honey Bee
Apis mellifera
XP_393469
725
82814
N313
H
R
I
V
R
L
I
N
S
Q
S
S
D
D
K
Nematode Worm
Caenorhab. elegans
NP_504199
730
81599
P322
I
N
N
L
D
D
N
P
T
F
N
G
V
Q
S
Sea Urchin
Strong. purpuratus
XP_780248
712
80030
L310
E
E
M
S
M
E
E
L
S
E
E
E
V
Q
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9SX03
768
85190
N323
M
L
G
G
V
E
K
N
L
K
N
G
T
H
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43299
716
80315
E308
K
K
K
Y
E
E
Y
E
F
Q
K
D
E
E
E
Baker's Yeast
Sacchar. cerevisiae
P38132
845
94857
K387
F
V
R
Q
H
K
K
K
F
A
S
F
S
L
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.1
98.4
96.2
N.A.
92.7
94.3
N.A.
N.A.
32.6
83.7
80.5
N.A.
31.1
63.1
49.1
70.7
Protein Similarity:
100
96.6
99.3
98.1
N.A.
97.6
98.3
N.A.
N.A.
50.2
92.9
90
N.A.
48.6
77.6
68.9
84.7
P-Site Identity:
100
100
100
80
N.A.
73.3
80
N.A.
N.A.
0
80
60
N.A.
6.6
0
0
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
80
86.6
N.A.
N.A.
20
86.6
66.6
N.A.
26.6
13.3
20
40
Percent
Protein Identity:
N.A.
32
N.A.
50.3
42.2
N.A.
Protein Similarity:
N.A.
52.8
N.A.
67
58.9
N.A.
P-Site Identity:
N.A.
6.6
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
40
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
7
0
7
0
7
38
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% C
% Asp:
0
7
0
0
7
7
0
0
13
50
50
7
7
13
0
% D
% Glu:
7
7
0
0
7
19
13
13
44
13
13
44
7
7
7
% E
% Phe:
7
0
0
0
0
0
0
7
13
7
0
7
0
0
0
% F
% Gly:
0
0
7
7
7
0
0
0
0
0
0
19
0
44
0
% G
% His:
7
0
0
7
7
7
0
0
0
0
0
0
0
7
7
% H
% Ile:
7
32
13
0
0
0
7
0
7
0
0
0
0
0
0
% I
% Lys:
7
7
7
50
0
7
63
7
0
13
13
0
7
0
7
% K
% Leu:
0
13
0
13
0
13
0
7
7
0
0
0
19
13
7
% L
% Met:
7
0
7
0
57
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
13
0
0
32
7
13
0
0
13
0
0
0
0
% N
% Pro:
7
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
7
0
0
0
0
0
13
0
0
0
13
7
% Q
% Arg:
38
7
7
0
13
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
7
7
0
7
0
7
0
44
13
0
13
7
44
0
7
% S
% Thr:
0
0
7
0
0
13
0
7
7
0
0
0
7
0
19
% T
% Val:
7
19
44
7
7
0
0
0
0
0
0
13
13
0
0
% V
% Trp:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
13
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _