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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM7
All Species:
31.52
Human Site:
S365
Identified Species:
46.22
UniProt:
P33993
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P33993
NP_005907.3
719
81308
S365
L
V
G
G
V
D
Q
S
P
R
G
M
K
I
R
Chimpanzee
Pan troglodytes
XP_527834
716
80774
S365
L
V
G
G
V
D
Q
S
P
R
G
M
K
I
R
Rhesus Macaque
Macaca mulatta
XP_001101053
719
81187
S365
L
V
G
G
V
D
Q
S
P
R
G
M
K
I
R
Dog
Lupus familis
XP_849809
719
81456
S365
L
V
G
G
V
D
Q
S
P
R
G
M
K
I
R
Cat
Felis silvestris
Mouse
Mus musculus
Q61881
719
81192
S365
L
V
G
G
V
D
Q
S
P
Q
G
M
K
I
R
Rat
Rattus norvegicus
NP_001004203
719
81044
S365
L
V
G
G
V
D
Q
S
P
Q
G
M
K
I
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZMN2
812
91233
G373
A
V
G
T
T
G
R
G
S
S
G
V
G
L
T
Frog
Xenopus laevis
Q91876
720
81860
S364
L
V
G
G
V
D
N
S
P
R
G
M
K
I
R
Zebra Danio
Brachydanio rerio
NP_997734
721
80978
A365
L
V
G
G
V
E
Q
A
P
R
G
M
K
I
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q26454
866
96592
K493
L
F
G
G
T
K
K
K
H
A
T
L
G
R
Q
Honey Bee
Apis mellifera
XP_393469
725
82814
H370
L
V
G
G
T
D
K
H
K
D
D
I
K
I
R
Nematode Worm
Caenorhab. elegans
NP_504199
730
81599
S374
L
V
G
G
N
D
N
S
S
N
G
M
K
I
R
Sea Urchin
Strong. purpuratus
XP_780248
712
80030
I362
R
S
P
K
G
M
K
I
R
G
N
I
N
I
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9SX03
768
85190
T374
G
S
S
G
V
G
L
T
A
A
V
T
S
D
Q
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43299
716
80315
L360
V
G
A
P
H
R
Q
L
K
D
G
M
K
I
R
Baker's Yeast
Sacchar. cerevisiae
P38132
845
94857
V444
V
G
G
V
D
K
R
V
G
D
G
M
K
I
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.1
98.4
96.2
N.A.
92.7
94.3
N.A.
N.A.
32.6
83.7
80.5
N.A.
31.1
63.1
49.1
70.7
Protein Similarity:
100
96.6
99.3
98.1
N.A.
97.6
98.3
N.A.
N.A.
50.2
92.9
90
N.A.
48.6
77.6
68.9
84.7
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
20
93.3
86.6
N.A.
20
53.3
73.3
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
40
93.3
100
N.A.
40
66.6
73.3
20
Percent
Protein Identity:
N.A.
32
N.A.
50.3
42.2
N.A.
Protein Similarity:
N.A.
52.8
N.A.
67
58.9
N.A.
P-Site Identity:
N.A.
13.3
N.A.
40
40
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
46.6
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
0
0
0
0
7
7
13
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% C
% Asp:
0
0
0
0
7
57
0
0
0
19
7
0
0
7
0
% D
% Glu:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
13
82
75
7
13
0
7
7
7
75
0
13
0
0
% G
% His:
0
0
0
0
7
0
0
7
7
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
7
0
0
0
13
0
82
0
% I
% Lys:
0
0
0
7
0
13
19
7
13
0
0
0
75
0
0
% K
% Leu:
69
0
0
0
0
0
7
7
0
0
0
7
0
7
0
% L
% Met:
0
0
0
0
0
7
0
0
0
0
0
69
0
0
0
% M
% Asn:
0
0
0
0
7
0
13
0
0
7
7
0
7
0
0
% N
% Pro:
0
0
7
7
0
0
0
0
50
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
50
0
0
13
0
0
0
0
13
% Q
% Arg:
7
0
0
0
0
7
13
0
7
38
0
0
0
7
75
% R
% Ser:
0
13
7
0
0
0
0
50
13
7
0
0
7
0
0
% S
% Thr:
0
0
0
7
19
0
0
7
0
0
7
7
0
0
7
% T
% Val:
13
69
0
7
57
0
0
7
0
0
7
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _