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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM7
All Species:
20.61
Human Site:
S549
Identified Species:
30.22
UniProt:
P33993
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P33993
NP_005907.3
719
81308
S549
Q
H
S
R
Q
P
P
S
Q
F
E
P
L
D
M
Chimpanzee
Pan troglodytes
XP_527834
716
80774
S549
Q
H
S
R
Q
P
P
S
Q
F
E
P
L
D
M
Rhesus Macaque
Macaca mulatta
XP_001101053
719
81187
S549
Q
H
S
R
Q
P
P
S
Q
F
E
P
L
D
M
Dog
Lupus familis
XP_849809
719
81456
A549
Q
H
S
R
Q
P
P
A
Q
F
E
P
L
D
M
Cat
Felis silvestris
Mouse
Mus musculus
Q61881
719
81192
A549
Q
H
S
R
Q
P
P
A
Q
F
E
P
L
D
M
Rat
Rattus norvegicus
NP_001004203
719
81044
A549
Q
H
S
R
Q
P
P
A
Q
F
E
P
L
D
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZMN2
812
91233
R559
L
L
H
G
P
N
R
R
K
E
K
I
V
S
M
Frog
Xenopus laevis
Q91876
720
81860
S548
Q
H
S
K
Q
P
P
S
Q
F
Q
P
L
D
M
Zebra Danio
Brachydanio rerio
NP_997734
721
80978
T549
Q
H
C
R
Q
P
P
T
H
F
T
P
I
D
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q26454
866
96592
E679
Y
Y
V
T
R
H
E
E
E
D
T
M
F
D
M
Honey Bee
Apis mellifera
XP_393469
725
82814
M554
Q
H
C
I
Q
P
P
M
Q
S
Q
A
L
D
M
Nematode Worm
Caenorhab. elegans
NP_504199
730
81599
E559
H
G
C
H
P
N
R
E
K
K
D
L
I
S
L
Sea Urchin
Strong. purpuratus
XP_780248
712
80030
T540
Q
H
C
K
Q
P
P
T
Q
V
N
P
L
H
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9SX03
768
85190
K549
R
R
R
G
K
K
S
K
Q
D
R
L
T
V
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43299
716
80315
L544
Q
T
E
E
S
P
A
L
G
F
E
P
L
E
P
Baker's Yeast
Sacchar. cerevisiae
P38132
845
94857
L628
M
H
N
K
Q
P
D
L
D
F
T
P
V
E
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.1
98.4
96.2
N.A.
92.7
94.3
N.A.
N.A.
32.6
83.7
80.5
N.A.
31.1
63.1
49.1
70.7
Protein Similarity:
100
96.6
99.3
98.1
N.A.
97.6
98.3
N.A.
N.A.
50.2
92.9
90
N.A.
48.6
77.6
68.9
84.7
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
6.6
86.6
66.6
N.A.
13.3
60
0
60
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
26.6
100
80
N.A.
33.3
66.6
26.6
73.3
Percent
Protein Identity:
N.A.
32
N.A.
50.3
42.2
N.A.
Protein Similarity:
N.A.
52.8
N.A.
67
58.9
N.A.
P-Site Identity:
N.A.
6.6
N.A.
40
33.3
N.A.
P-Site Similarity:
N.A.
20
N.A.
46.6
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
7
19
0
0
0
7
0
0
0
% A
% Cys:
0
0
25
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
7
0
7
13
7
0
0
63
0
% D
% Glu:
0
0
7
7
0
0
7
13
7
7
44
0
0
13
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
63
0
0
7
0
0
% F
% Gly:
0
7
0
13
0
0
0
0
7
0
0
0
0
0
0
% G
% His:
7
69
7
7
0
7
0
0
7
0
0
0
0
7
0
% H
% Ile:
0
0
0
7
0
0
0
0
0
0
0
7
13
0
0
% I
% Lys:
0
0
0
19
7
7
0
7
13
7
7
0
0
0
7
% K
% Leu:
7
7
0
0
0
0
0
13
0
0
0
13
63
0
7
% L
% Met:
7
0
0
0
0
0
0
7
0
0
0
7
0
0
75
% M
% Asn:
0
0
7
0
0
13
0
0
0
0
7
0
0
0
0
% N
% Pro:
0
0
0
0
13
75
63
0
0
0
0
69
0
0
13
% P
% Gln:
69
0
0
0
69
0
0
0
63
0
13
0
0
0
0
% Q
% Arg:
7
7
7
44
7
0
13
7
0
0
7
0
0
0
0
% R
% Ser:
0
0
44
0
7
0
7
25
0
7
0
0
0
13
0
% S
% Thr:
0
7
0
7
0
0
0
13
0
0
19
0
7
0
0
% T
% Val:
0
0
7
0
0
0
0
0
0
7
0
0
13
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _