KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM7
All Species:
34.55
Human Site:
S595
Identified Species:
50.67
UniProt:
P33993
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P33993
NP_005907.3
719
81308
S595
M
R
R
E
A
W
A
S
K
D
A
T
Y
T
S
Chimpanzee
Pan troglodytes
XP_527834
716
80774
S595
M
R
R
E
A
W
A
S
K
D
A
T
Y
T
S
Rhesus Macaque
Macaca mulatta
XP_001101053
719
81187
S595
M
R
R
E
A
W
A
S
K
D
A
T
Y
T
S
Dog
Lupus familis
XP_849809
719
81456
S595
M
R
R
E
A
W
A
S
K
D
A
T
Y
T
S
Cat
Felis silvestris
Mouse
Mus musculus
Q61881
719
81192
S595
M
R
R
E
A
R
A
S
K
D
A
T
Y
T
S
Rat
Rattus norvegicus
NP_001004203
719
81044
S595
M
R
R
E
A
R
A
S
K
D
A
T
Y
T
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZMN2
812
91233
N605
L
R
S
Q
N
Q
M
N
S
D
I
A
R
T
S
Frog
Xenopus laevis
Q91876
720
81860
N594
M
R
K
E
A
R
T
N
K
D
M
T
F
T
S
Zebra Danio
Brachydanio rerio
NP_997734
721
80978
S595
M
R
K
E
A
R
V
S
K
D
T
T
F
T
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q26454
866
96592
G725
D
M
R
K
V
G
A
G
R
G
Q
I
S
A
Y
Honey Bee
Apis mellifera
XP_393469
725
82814
G600
M
R
R
A
A
R
N
G
E
D
K
T
F
T
S
Nematode Worm
Caenorhab. elegans
NP_504199
730
81599
S605
M
R
R
D
A
R
Y
S
S
D
P
T
F
V
S
Sea Urchin
Strong. purpuratus
XP_780248
712
80030
S586
M
R
K
E
A
R
G
S
K
D
S
T
F
T
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9SX03
768
85190
A595
L
R
D
G
S
A
N
A
K
S
G
G
G
T
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43299
716
80315
S590
I
R
Q
E
E
A
K
S
N
T
P
H
S
Y
T
Baker's Yeast
Sacchar. cerevisiae
P38132
845
94857
E674
L
R
Q
D
S
K
R
E
M
D
S
K
F
S
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.1
98.4
96.2
N.A.
92.7
94.3
N.A.
N.A.
32.6
83.7
80.5
N.A.
31.1
63.1
49.1
70.7
Protein Similarity:
100
96.6
99.3
98.1
N.A.
97.6
98.3
N.A.
N.A.
50.2
92.9
90
N.A.
48.6
77.6
68.9
84.7
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
26.6
60
66.6
N.A.
13.3
53.3
53.3
66.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
46.6
80
80
N.A.
26.6
66.6
66.6
86.6
Percent
Protein Identity:
N.A.
32
N.A.
50.3
42.2
N.A.
Protein Similarity:
N.A.
52.8
N.A.
67
58.9
N.A.
P-Site Identity:
N.A.
20
N.A.
20
13.3
N.A.
P-Site Similarity:
N.A.
40
N.A.
40
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
69
13
44
7
0
0
38
7
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
7
13
0
0
0
0
0
82
0
0
0
0
0
% D
% Glu:
0
0
0
63
7
0
0
7
7
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
38
0
7
% F
% Gly:
0
0
0
7
0
7
7
13
0
7
7
7
7
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% H
% Ile:
7
0
0
0
0
0
0
0
0
0
7
7
0
0
0
% I
% Lys:
0
0
19
7
0
7
7
0
63
0
7
7
0
0
0
% K
% Leu:
19
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% L
% Met:
69
7
0
0
0
0
7
0
7
0
7
0
0
0
0
% M
% Asn:
0
0
0
0
7
0
13
13
7
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% P
% Gln:
0
0
13
7
0
7
0
0
0
0
7
0
0
0
0
% Q
% Arg:
0
94
57
0
0
44
7
0
7
0
0
0
7
0
0
% R
% Ser:
0
0
7
0
13
0
0
63
13
7
13
0
13
7
75
% S
% Thr:
0
0
0
0
0
0
7
0
0
7
7
69
0
75
7
% T
% Val:
0
0
0
0
7
0
7
0
0
0
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
25
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
0
0
0
0
0
38
7
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _