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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM7
All Species:
34.55
Human Site:
S674
Identified Species:
50.67
UniProt:
P33993
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P33993
NP_005907.3
719
81308
S674
E
L
V
S
G
G
R
S
V
R
F
S
E
A
E
Chimpanzee
Pan troglodytes
XP_527834
716
80774
S671
E
L
V
S
G
G
R
S
V
R
F
S
E
A
E
Rhesus Macaque
Macaca mulatta
XP_001101053
719
81187
S674
E
L
V
S
G
G
R
S
V
R
F
S
E
A
E
Dog
Lupus familis
XP_849809
719
81456
S674
E
L
V
S
E
G
R
S
V
R
F
S
E
A
E
Cat
Felis silvestris
Mouse
Mus musculus
Q61881
719
81192
S674
E
L
V
S
R
G
R
S
V
H
F
S
E
A
E
Rat
Rattus norvegicus
NP_001004203
719
81044
S674
E
L
V
S
G
G
R
S
V
R
F
S
E
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZMN2
812
91233
T675
Q
V
E
D
D
S
E
T
E
K
E
E
E
E
E
Frog
Xenopus laevis
Q91876
720
81860
S675
V
P
E
K
G
A
R
S
V
K
Y
S
E
A
E
Zebra Danio
Brachydanio rerio
NP_997734
721
80978
S676
C
G
E
S
A
G
R
S
V
R
V
S
A
A
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q26454
866
96592
A795
L
T
T
G
L
S
T
A
A
R
K
K
R
A
D
Honey Bee
Apis mellifera
XP_393469
725
82814
T680
E
L
A
G
D
K
K
T
V
K
V
S
D
I
L
Nematode Worm
Caenorhab. elegans
NP_504199
730
81599
A684
E
L
Y
H
A
D
N
A
P
I
A
I
S
N
A
Sea Urchin
Strong. purpuratus
XP_780248
712
80030
S667
I
S
E
Q
S
G
R
S
I
K
Y
T
E
A
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9SX03
768
85190
D721
H
V
L
A
N
H
I
D
Q
M
S
I
D
E
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43299
716
80315
H671
A
A
R
S
K
K
T
H
V
S
Y
A
N
A
L
Baker's Yeast
Sacchar. cerevisiae
P38132
845
94857
K757
K
M
L
Q
E
T
G
K
N
T
L
S
Y
E
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.1
98.4
96.2
N.A.
92.7
94.3
N.A.
N.A.
32.6
83.7
80.5
N.A.
31.1
63.1
49.1
70.7
Protein Similarity:
100
96.6
99.3
98.1
N.A.
97.6
98.3
N.A.
N.A.
50.2
92.9
90
N.A.
48.6
77.6
68.9
84.7
P-Site Identity:
100
100
100
93.3
N.A.
86.6
100
N.A.
N.A.
13.3
53.3
60
N.A.
13.3
26.6
13.3
33.3
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
100
N.A.
N.A.
40
66.6
60
N.A.
26.6
53.3
20
60
Percent
Protein Identity:
N.A.
32
N.A.
50.3
42.2
N.A.
Protein Similarity:
N.A.
52.8
N.A.
67
58.9
N.A.
P-Site Identity:
N.A.
0
N.A.
20
6.6
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
33.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
7
7
13
7
0
13
7
0
7
7
7
69
7
% A
% Cys:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
7
13
7
0
7
0
0
0
0
13
0
7
% D
% Glu:
50
0
25
0
13
0
7
0
7
0
7
7
57
19
57
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
38
0
0
0
0
% F
% Gly:
0
7
0
13
32
50
7
0
0
0
0
0
0
0
0
% G
% His:
7
0
0
7
0
7
0
7
0
7
0
0
0
0
0
% H
% Ile:
7
0
0
0
0
0
7
0
7
7
0
13
0
7
7
% I
% Lys:
7
0
0
7
7
13
7
7
0
25
7
7
0
0
0
% K
% Leu:
7
50
13
0
7
0
0
0
0
0
7
0
0
0
13
% L
% Met:
0
7
0
0
0
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
0
0
0
7
0
7
0
7
0
0
0
7
7
7
% N
% Pro:
0
7
0
0
0
0
0
0
7
0
0
0
0
0
0
% P
% Gln:
7
0
0
13
0
0
0
0
7
0
0
0
0
0
0
% Q
% Arg:
0
0
7
0
7
0
57
0
0
44
0
0
7
0
7
% R
% Ser:
0
7
0
50
7
13
0
57
0
7
7
63
7
0
0
% S
% Thr:
0
7
7
0
0
7
13
13
0
7
0
7
0
0
0
% T
% Val:
7
13
38
0
0
0
0
0
63
0
13
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
0
0
0
0
0
19
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _