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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM7
All Species:
31.52
Human Site:
S686
Identified Species:
46.22
UniProt:
P33993
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P33993
NP_005907.3
719
81308
S686
E
A
E
Q
R
C
V
S
R
G
F
T
P
A
Q
Chimpanzee
Pan troglodytes
XP_527834
716
80774
S683
E
A
E
Q
R
C
V
S
R
G
F
T
P
A
Q
Rhesus Macaque
Macaca mulatta
XP_001101053
719
81187
S686
E
A
E
Q
R
C
I
S
R
G
F
T
P
A
Q
Dog
Lupus familis
XP_849809
719
81456
S686
E
A
E
Q
R
C
I
S
R
G
F
T
P
A
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q61881
719
81192
S686
E
A
E
Q
R
C
I
S
R
G
F
T
P
A
Q
Rat
Rattus norvegicus
NP_001004203
719
81044
S686
E
A
E
Q
R
C
I
S
R
G
F
T
P
A
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZMN2
812
91233
E687
E
E
E
E
T
Q
P
E
K
E
G
R
K
Q
R
Frog
Xenopus laevis
Q91876
720
81860
S687
E
A
E
Q
R
C
V
S
K
G
F
T
P
A
Q
Zebra Danio
Brachydanio rerio
NP_997734
721
80978
S688
A
A
E
Q
R
C
V
S
R
G
F
T
P
A
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q26454
866
96592
I807
R
A
D
L
V
A
A
I
K
E
N
L
K
K
K
Honey Bee
Apis mellifera
XP_393469
725
82814
N692
D
I
L
E
R
C
T
N
K
G
F
K
P
D
E
Nematode Worm
Caenorhab. elegans
NP_504199
730
81599
A696
S
N
A
I
Q
R
C
A
R
K
G
I
S
E
V
Sea Urchin
Strong. purpuratus
XP_780248
712
80030
A679
E
A
R
Q
A
C
L
A
K
G
Y
T
N
D
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9SX03
768
85190
N733
D
E
I
E
Q
M
V
N
R
E
S
T
A
P
Y
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43299
716
80315
R683
N
A
L
N
W
I
S
R
K
G
Y
S
E
A
Q
Baker's Yeast
Sacchar. cerevisiae
P38132
845
94857
V769
Y
E
N
I
V
K
T
V
R
L
R
G
F
T
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.1
98.4
96.2
N.A.
92.7
94.3
N.A.
N.A.
32.6
83.7
80.5
N.A.
31.1
63.1
49.1
70.7
Protein Similarity:
100
96.6
99.3
98.1
N.A.
97.6
98.3
N.A.
N.A.
50.2
92.9
90
N.A.
48.6
77.6
68.9
84.7
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
13.3
93.3
93.3
N.A.
6.6
33.3
6.6
46.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
33.3
100
93.3
N.A.
26.6
66.6
20
73.3
Percent
Protein Identity:
N.A.
32
N.A.
50.3
42.2
N.A.
Protein Similarity:
N.A.
52.8
N.A.
67
58.9
N.A.
P-Site Identity:
N.A.
20
N.A.
26.6
6.6
N.A.
P-Site Similarity:
N.A.
46.6
N.A.
46.6
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
69
7
0
7
7
7
13
0
0
0
0
7
57
0
% A
% Cys:
0
0
0
0
0
63
7
0
0
0
0
0
0
0
0
% C
% Asp:
13
0
7
0
0
0
0
0
0
0
0
0
0
13
0
% D
% Glu:
57
19
57
19
0
0
0
7
0
19
0
0
7
7
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
57
0
7
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
69
13
7
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
7
13
0
7
25
7
0
0
0
7
0
0
0
% I
% Lys:
0
0
0
0
0
7
0
0
38
7
0
7
13
7
7
% K
% Leu:
0
0
13
7
0
0
7
0
0
7
0
7
0
0
0
% L
% Met:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
7
% M
% Asn:
7
7
7
7
0
0
0
13
0
0
7
0
7
0
0
% N
% Pro:
0
0
0
0
0
0
7
0
0
0
0
0
57
7
0
% P
% Gln:
0
0
0
57
13
7
0
0
0
0
0
0
0
7
63
% Q
% Arg:
7
0
7
0
57
7
0
7
63
0
7
7
0
0
7
% R
% Ser:
7
0
0
0
0
0
7
50
0
0
7
7
7
0
0
% S
% Thr:
0
0
0
0
7
0
13
0
0
0
0
63
0
7
0
% T
% Val:
0
0
0
0
13
0
32
7
0
0
0
0
0
0
7
% V
% Trp:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
0
0
0
13
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _