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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM7
All Species:
31.82
Human Site:
Y221
Identified Species:
46.67
UniProt:
P33993
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P33993
NP_005907.3
719
81308
Y221
N
R
S
G
G
R
L
Y
L
Q
T
R
G
S
R
Chimpanzee
Pan troglodytes
XP_527834
716
80774
Y221
N
R
S
G
G
R
L
Y
L
Q
T
R
G
S
R
Rhesus Macaque
Macaca mulatta
XP_001101053
719
81187
Y221
N
R
S
G
G
R
L
Y
L
Q
T
R
G
S
K
Dog
Lupus familis
XP_849809
719
81456
Y221
N
R
S
G
G
R
L
Y
L
Q
T
R
G
S
K
Cat
Felis silvestris
Mouse
Mus musculus
Q61881
719
81192
Y221
N
R
S
G
G
R
L
Y
L
Q
T
R
G
S
K
Rat
Rattus norvegicus
NP_001004203
719
81044
Y221
N
R
S
G
G
R
L
Y
L
Q
T
R
G
S
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZMN2
812
91233
D225
V
D
V
I
L
D
D
D
L
V
D
K
V
K
P
Frog
Xenopus laevis
Q91876
720
81860
Y220
N
R
S
G
G
R
L
Y
L
Q
T
R
G
S
K
Zebra Danio
Brachydanio rerio
NP_997734
721
80978
Y221
N
K
S
G
G
R
L
Y
L
Q
T
R
G
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q26454
866
96592
R346
C
F
R
L
I
H
N
R
S
E
F
T
D
K
Q
Honey Bee
Apis mellifera
XP_393469
725
82814
D225
N
K
S
G
G
V
L
D
M
Q
T
R
G
S
K
Nematode Worm
Caenorhab. elegans
NP_504199
730
81599
H234
A
K
A
N
G
R
L
H
M
Q
L
R
G
S
K
Sea Urchin
Strong. purpuratus
XP_780248
712
80030
K222
T
R
G
S
K
F
V
K
F
Q
E
V
K
I
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9SX03
768
85190
G235
G
D
R
V
S
I
V
G
V
Y
K
A
L
P
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43299
716
80315
A220
N
P
I
L
Q
L
R
A
S
K
F
L
K
F
Q
Baker's Yeast
Sacchar. cerevisiae
P38132
845
94857
F299
N
Q
T
K
G
Q
L
F
M
S
T
R
A
S
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.1
98.4
96.2
N.A.
92.7
94.3
N.A.
N.A.
32.6
83.7
80.5
N.A.
31.1
63.1
49.1
70.7
Protein Similarity:
100
96.6
99.3
98.1
N.A.
97.6
98.3
N.A.
N.A.
50.2
92.9
90
N.A.
48.6
77.6
68.9
84.7
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
6.6
93.3
86.6
N.A.
0
66.6
46.6
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
13.3
100
100
N.A.
13.3
86.6
80
26.6
Percent
Protein Identity:
N.A.
32
N.A.
50.3
42.2
N.A.
Protein Similarity:
N.A.
52.8
N.A.
67
58.9
N.A.
P-Site Identity:
N.A.
0
N.A.
6.6
40
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
20
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
0
0
0
0
7
0
0
0
7
7
0
0
% A
% Cys:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
13
0
0
0
7
7
13
0
0
7
0
7
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
7
7
0
0
0
0
% E
% Phe:
0
7
0
0
0
7
0
7
7
0
13
0
0
7
0
% F
% Gly:
7
0
7
57
69
0
0
7
0
0
0
0
63
0
7
% G
% His:
0
0
0
0
0
7
0
7
0
0
0
0
0
0
0
% H
% Ile:
0
0
7
7
7
7
0
0
0
0
0
0
0
7
0
% I
% Lys:
0
19
0
7
7
0
0
7
0
7
7
7
13
13
57
% K
% Leu:
0
0
0
13
7
7
69
0
57
0
7
7
7
0
0
% L
% Met:
0
0
0
0
0
0
0
0
19
0
0
0
0
0
0
% M
% Asn:
69
0
0
7
0
0
7
0
0
0
0
0
0
0
0
% N
% Pro:
0
7
0
0
0
0
0
0
0
0
0
0
0
7
7
% P
% Gln:
0
7
0
0
7
7
0
0
0
69
0
0
0
0
19
% Q
% Arg:
0
50
13
0
0
57
7
7
0
0
0
69
0
0
13
% R
% Ser:
0
0
57
7
7
0
0
0
13
7
0
0
0
69
0
% S
% Thr:
7
0
7
0
0
0
0
0
0
0
63
7
0
0
0
% T
% Val:
7
0
7
7
0
7
13
0
7
7
0
7
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _