Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MCM7 All Species: 30.61
Human Site: Y33 Identified Species: 44.89
UniProt: P33993 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P33993 NP_005907.3 719 81308 Y33 L G K K Q F K Y G N Q L V R L
Chimpanzee Pan troglodytes XP_527834 716 80774 Y33 L G K K Q F K Y G N Q L V R L
Rhesus Macaque Macaca mulatta XP_001101053 719 81187 Y33 L G K K Q F K Y G N Q L V R L
Dog Lupus familis XP_849809 719 81456 Y33 Y G K K Q F K Y G N Q L V Q L
Cat Felis silvestris
Mouse Mus musculus Q61881 719 81192 Y33 L G K K Q F K Y G T Q L V H L
Rat Rattus norvegicus NP_001004203 719 81044 Y33 L G K K Q F K Y G T Q L V H L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZMN2 812 91233 Y33 D E E D Q G V Y H G K V R D M
Frog Xenopus laevis Q91876 720 81860 G33 G K K H F K Y G V Q L A N I A
Zebra Danio Brachydanio rerio NP_997734 721 80978 Y33 S G K K I F K Y G A Q L V S L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q26454 866 96592 T139 I P E K G S E T T D P V S E S
Honey Bee Apis mellifera XP_393469 725 82814 K36 V T D E K T F K Y R K Q L T N
Nematode Worm Caenorhab. elegans NP_504199 730 81599 P37 D G S G K A F P Y R D Q V F E
Sea Urchin Strong. purpuratus XP_780248 712 80030 K33 R K G K K D F K Y A Q Q L V S
Poplar Tree Populus trichocarpa
Maize Zea mays Q9SX03 768 85190 V36 M Q A V R D M V Q N K R H R L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P43299 716 80315 L33 R S K Y M E I L Q E V S N R K
Baker's Yeast Sacchar. cerevisiae P38132 845 94857 Y63 L L E K G P K Y M A M L Q K V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.1 98.4 96.2 N.A. 92.7 94.3 N.A. N.A. 32.6 83.7 80.5 N.A. 31.1 63.1 49.1 70.7
Protein Similarity: 100 96.6 99.3 98.1 N.A. 97.6 98.3 N.A. N.A. 50.2 92.9 90 N.A. 48.6 77.6 68.9 84.7
P-Site Identity: 100 100 100 86.6 N.A. 86.6 86.6 N.A. N.A. 13.3 6.6 73.3 N.A. 6.6 0 13.3 13.3
P-Site Similarity: 100 100 100 93.3 N.A. 86.6 86.6 N.A. N.A. 40 6.6 73.3 N.A. 40 33.3 20 26.6
Percent
Protein Identity: N.A. 32 N.A. 50.3 42.2 N.A.
Protein Similarity: N.A. 52.8 N.A. 67 58.9 N.A.
P-Site Identity: N.A. 20 N.A. 13.3 33.3 N.A.
P-Site Similarity: N.A. 40 N.A. 13.3 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 0 0 7 0 0 0 19 0 7 0 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 13 0 7 7 0 13 0 0 0 7 7 0 0 7 0 % D
% Glu: 0 7 19 7 0 7 7 0 0 7 0 0 0 7 7 % E
% Phe: 0 0 0 0 7 44 19 0 0 0 0 0 0 7 0 % F
% Gly: 7 50 7 7 13 7 0 7 44 7 0 0 0 0 0 % G
% His: 0 0 0 7 0 0 0 0 7 0 0 0 7 13 0 % H
% Ile: 7 0 0 0 7 0 7 0 0 0 0 0 0 7 0 % I
% Lys: 0 13 57 63 19 7 50 13 0 0 19 0 0 7 7 % K
% Leu: 38 7 0 0 0 0 0 7 0 0 7 50 13 0 50 % L
% Met: 7 0 0 0 7 0 7 0 7 0 7 0 0 0 7 % M
% Asn: 0 0 0 0 0 0 0 0 0 32 0 0 13 0 7 % N
% Pro: 0 7 0 0 0 7 0 7 0 0 7 0 0 0 0 % P
% Gln: 0 7 0 0 44 0 0 0 13 7 50 19 7 7 0 % Q
% Arg: 13 0 0 0 7 0 0 0 0 13 0 7 7 32 0 % R
% Ser: 7 7 7 0 0 7 0 0 0 0 0 7 7 7 13 % S
% Thr: 0 7 0 0 0 7 0 7 7 13 0 0 0 7 0 % T
% Val: 7 0 0 7 0 0 7 7 7 0 7 13 50 7 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 7 0 0 7 57 19 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _