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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM7
All Species:
46.67
Human Site:
Y580
Identified Species:
68.44
UniProt:
P33993
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P33993
NP_005907.3
719
81308
Y580
V
P
E
S
L
A
D
Y
I
T
A
A
Y
V
E
Chimpanzee
Pan troglodytes
XP_527834
716
80774
Y580
V
P
E
S
L
A
D
Y
I
T
A
A
Y
V
E
Rhesus Macaque
Macaca mulatta
XP_001101053
719
81187
Y580
V
P
E
S
L
A
D
Y
I
T
A
A
Y
V
E
Dog
Lupus familis
XP_849809
719
81456
Y580
V
P
E
S
L
A
D
Y
I
T
A
A
Y
V
E
Cat
Felis silvestris
Mouse
Mus musculus
Q61881
719
81192
Y580
V
P
E
S
L
A
D
Y
I
T
A
A
Y
V
E
Rat
Rattus norvegicus
NP_001004203
719
81044
Y580
V
P
D
S
L
A
D
Y
I
T
A
A
Y
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZMN2
812
91233
Y590
L
T
Q
E
S
A
D
Y
I
A
E
E
Y
S
S
Frog
Xenopus laevis
Q91876
720
81860
Y579
I
P
E
A
L
A
D
Y
L
T
A
A
Y
V
E
Zebra Danio
Brachydanio rerio
NP_997734
721
80978
Y580
V
P
E
S
L
S
D
Y
I
T
A
A
Y
V
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q26454
866
96592
Q710
T
L
S
D
E
A
Q
Q
R
L
I
Q
A
Y
V
Honey Bee
Apis mellifera
XP_393469
725
82814
Y585
I
P
E
E
L
T
D
Y
I
V
E
S
Y
V
E
Nematode Worm
Caenorhab. elegans
NP_504199
730
81599
R590
V
D
P
A
L
R
E
R
I
V
E
A
Y
V
E
Sea Urchin
Strong. purpuratus
XP_780248
712
80030
Y571
I
P
E
A
L
T
D
Y
I
T
G
A
Y
V
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9SX03
768
85190
H580
L
T
D
E
A
S
D
H
I
A
T
S
Y
A
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43299
716
80315
Y575
V
P
A
E
L
E
E
Y
I
A
T
A
Y
S
S
Baker's Yeast
Sacchar. cerevisiae
P38132
845
94857
Y659
M
S
E
A
V
N
D
Y
V
V
Q
A
Y
I
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.1
98.4
96.2
N.A.
92.7
94.3
N.A.
N.A.
32.6
83.7
80.5
N.A.
31.1
63.1
49.1
70.7
Protein Similarity:
100
96.6
99.3
98.1
N.A.
97.6
98.3
N.A.
N.A.
50.2
92.9
90
N.A.
48.6
77.6
68.9
84.7
P-Site Identity:
100
100
100
100
N.A.
100
93.3
N.A.
N.A.
33.3
80
93.3
N.A.
6.6
60
46.6
73.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
46.6
100
100
N.A.
6.6
73.3
60
86.6
Percent
Protein Identity:
N.A.
32
N.A.
50.3
42.2
N.A.
Protein Similarity:
N.A.
52.8
N.A.
67
58.9
N.A.
P-Site Identity:
N.A.
26.6
N.A.
46.6
33.3
N.A.
P-Site Similarity:
N.A.
60
N.A.
53.3
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
25
7
57
0
0
0
19
50
75
7
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
13
7
0
0
82
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
63
25
7
7
13
0
0
0
19
7
0
0
75
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% H
% Ile:
19
0
0
0
0
0
0
0
82
0
7
0
0
7
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
13
7
0
0
75
0
0
0
7
7
0
0
0
0
0
% L
% Met:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
69
7
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
7
0
0
0
7
7
0
0
7
7
0
0
0
% Q
% Arg:
0
0
0
0
0
7
0
7
7
0
0
0
0
0
7
% R
% Ser:
0
7
7
44
7
13
0
0
0
0
0
13
0
13
13
% S
% Thr:
7
13
0
0
0
13
0
0
0
57
13
0
0
0
0
% T
% Val:
57
0
0
0
7
0
0
0
7
19
0
0
0
69
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
82
0
0
0
0
94
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _