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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPHX2
All Species:
21.82
Human Site:
T172
Identified Species:
48
UniProt:
P34913
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P34913
NP_001970.2
555
62616
T172
I
Y
K
F
L
L
D
T
L
K
A
S
P
S
E
Chimpanzee
Pan troglodytes
XP_001163779
555
62479
T172
I
Y
K
F
L
L
D
T
L
K
A
S
P
S
E
Rhesus Macaque
Macaca mulatta
XP_001109474
556
62466
T172
I
Y
R
F
L
L
D
T
L
K
A
S
P
S
E
Dog
Lupus familis
XP_534566
556
61919
T172
I
Y
K
F
V
L
D
T
L
K
A
S
P
S
E
Cat
Felis silvestris
Mouse
Mus musculus
P34914
554
62497
T172
I
Y
N
F
L
L
D
T
L
K
A
K
P
N
E
Rat
Rattus norvegicus
P80299
554
62322
T172
I
Y
K
F
V
L
D
T
L
K
A
K
P
N
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521600
530
58804
K150
D
T
A
A
A
L
E
K
L
E
Q
V
T
G
M
Chicken
Gallus gallus
NP_001028817
562
63232
V172
I
Y
T
Y
A
L
E
V
L
Q
A
Q
P
Q
E
Frog
Xenopus laevis
NP_001087143
560
62571
L173
I
Y
E
Y
A
L
K
L
L
H
A
K
P
K
E
Zebra Danio
Brachydanio rerio
NP_001008642
557
61874
K170
F
F
K
H
A
L
E
K
L
A
V
K
P
Q
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001121538
562
63381
K175
I
F
N
E
A
L
K
K
L
G
V
K
A
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
93.5
78.4
N.A.
73.1
72.9
N.A.
55.3
55.5
55.8
49.1
N.A.
N.A.
N.A.
N.A.
44.3
Protein Similarity:
100
99.8
96.9
89.3
N.A.
86.6
86.6
N.A.
69
74.5
73
67.6
N.A.
N.A.
N.A.
N.A.
63.3
P-Site Identity:
100
100
93.3
93.3
N.A.
80
80
N.A.
13.3
46.6
46.6
33.3
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
100
100
100
N.A.
86.6
93.3
N.A.
26.6
66.6
60
46.6
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
46
0
0
0
0
10
73
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
55
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
10
10
0
0
28
0
0
10
0
0
0
10
91
% E
% Phe:
10
19
0
55
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% G
% His:
0
0
0
10
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
82
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
46
0
0
0
19
28
0
55
0
46
0
10
0
% K
% Leu:
0
0
0
0
37
100
0
10
100
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
19
0
0
0
0
0
0
0
0
0
0
19
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
82
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
10
10
0
19
0
% Q
% Arg:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
37
0
37
0
% S
% Thr:
0
10
10
0
0
0
0
55
0
0
0
0
10
0
0
% T
% Val:
0
0
0
0
19
0
0
10
0
0
19
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
73
0
19
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _