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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EPHX2 All Species: 23.03
Human Site: T243 Identified Species: 50.67
UniProt: P34913 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P34913 NP_001970.2 555 62616 T243 D M S H G Y V T V K P R V R L
Chimpanzee Pan troglodytes XP_001163779 555 62479 T243 D M S H G Y V T V K P G V R L
Rhesus Macaque Macaca mulatta XP_001109474 556 62466 T243 D V S H G Y V T I K P G V R L
Dog Lupus familis XP_534566 556 61919 P243 D M S H V Y V P I K P G V R L
Cat Felis silvestris
Mouse Mus musculus P34914 554 62497 T241 D V S H G Y V T V K P G I R L
Rat Rattus norvegicus P80299 554 62322 T241 D V S H G Y V T V K P G I R L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521600 530 58804 Q218 S W F S W R Y Q I P A L A D A
Chicken Gallus gallus NP_001028817 562 63232 P243 T M S H G Y V P I R P G V Q L
Frog Xenopus laevis NP_001087143 560 62571 T244 K V T H G F V T V K P G V K L
Zebra Danio Brachydanio rerio NP_001008642 557 61874 N239 K V S H G Y V N I K P G V K I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_001121538 562 63381 T244 R V P H S Y A T T R S G V K F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 93.5 78.4 N.A. 73.1 72.9 N.A. 55.3 55.5 55.8 49.1 N.A. N.A. N.A. N.A. 44.3
Protein Similarity: 100 99.8 96.9 89.3 N.A. 86.6 86.6 N.A. 69 74.5 73 67.6 N.A. N.A. N.A. N.A. 63.3
P-Site Identity: 100 93.3 80 73.3 N.A. 80 80 N.A. 0 60 60 53.3 N.A. N.A. N.A. N.A. 26.6
P-Site Similarity: 100 93.3 93.3 80 N.A. 93.3 93.3 N.A. 6.6 80 86.6 80 N.A. N.A. N.A. N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 10 0 0 0 10 0 10 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 55 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 10 0 0 10 0 0 0 0 0 0 0 0 10 % F
% Gly: 0 0 0 0 73 0 0 0 0 0 0 82 0 0 0 % G
% His: 0 0 0 91 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 46 0 0 0 19 0 10 % I
% Lys: 19 0 0 0 0 0 0 0 0 73 0 0 0 28 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 73 % L
% Met: 0 37 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % N
% Pro: 0 0 10 0 0 0 0 19 0 10 82 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 10 0 0 0 0 0 10 0 % Q
% Arg: 10 0 0 0 0 10 0 0 0 19 0 10 0 55 0 % R
% Ser: 10 0 73 10 10 0 0 0 0 0 10 0 0 0 0 % S
% Thr: 10 0 10 0 0 0 0 64 10 0 0 0 0 0 0 % T
% Val: 0 55 0 0 10 0 82 0 46 0 0 0 73 0 0 % V
% Trp: 0 10 0 0 10 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 82 10 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _