KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPHX2
All Species:
30.3
Human Site:
Y166
Identified Species:
66.67
UniProt:
P34913
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P34913
NP_001970.2
555
62616
Y166
V
K
P
E
P
Q
I
Y
K
F
L
L
D
T
L
Chimpanzee
Pan troglodytes
XP_001163779
555
62479
Y166
V
K
P
E
P
Q
I
Y
K
F
L
L
D
T
L
Rhesus Macaque
Macaca mulatta
XP_001109474
556
62466
Y166
V
K
P
E
P
Q
I
Y
R
F
L
L
D
T
L
Dog
Lupus familis
XP_534566
556
61919
Y166
A
K
P
D
P
Q
I
Y
K
F
V
L
D
T
L
Cat
Felis silvestris
Mouse
Mus musculus
P34914
554
62497
Y166
I
K
P
E
P
Q
I
Y
N
F
L
L
D
T
L
Rat
Rattus norvegicus
P80299
554
62322
Y166
I
K
P
E
P
Q
I
Y
K
F
V
L
D
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521600
530
58804
T144
V
T
V
Q
A
R
D
T
A
A
A
L
E
K
L
Chicken
Gallus gallus
NP_001028817
562
63232
Y166
H
K
P
D
P
R
I
Y
T
Y
A
L
E
V
L
Frog
Xenopus laevis
NP_001087143
560
62571
Y167
R
K
P
E
T
Q
I
Y
E
Y
A
L
K
L
L
Zebra Danio
Brachydanio rerio
NP_001008642
557
61874
F164
R
I
P
E
P
D
F
F
K
H
A
L
E
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001121538
562
63381
F169
R
K
P
D
Q
S
I
F
N
E
A
L
K
K
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
93.5
78.4
N.A.
73.1
72.9
N.A.
55.3
55.5
55.8
49.1
N.A.
N.A.
N.A.
N.A.
44.3
Protein Similarity:
100
99.8
96.9
89.3
N.A.
86.6
86.6
N.A.
69
74.5
73
67.6
N.A.
N.A.
N.A.
N.A.
63.3
P-Site Identity:
100
100
93.3
80
N.A.
86.6
86.6
N.A.
20
46.6
53.3
40
N.A.
N.A.
N.A.
N.A.
33.3
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
100
N.A.
40
73.3
66.6
53.3
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
10
0
0
0
10
10
46
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
28
0
10
10
0
0
0
0
0
55
0
0
% D
% Glu:
0
0
0
64
0
0
0
0
10
10
0
0
28
0
0
% E
% Phe:
0
0
0
0
0
0
10
19
0
55
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
19
10
0
0
0
0
82
0
0
0
0
0
0
0
0
% I
% Lys:
0
82
0
0
0
0
0
0
46
0
0
0
19
28
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
37
100
0
10
100
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
19
0
0
0
0
0
0
% N
% Pro:
0
0
91
0
73
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
10
10
64
0
0
0
0
0
0
0
0
0
% Q
% Arg:
28
0
0
0
0
19
0
0
10
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
10
0
0
10
0
0
10
10
0
0
0
0
55
0
% T
% Val:
37
0
10
0
0
0
0
0
0
0
19
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
73
0
19
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _