KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RYK
All Species:
25.45
Human Site:
S435
Identified Species:
56
UniProt:
P34925
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P34925
NP_001005861.1
604
67507
S435
A
N
N
P
Q
A
I
S
Q
Q
D
L
V
H
M
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001112355
765
84687
S596
A
N
N
P
Q
A
I
S
Q
Q
D
L
V
H
M
Dog
Lupus familis
XP_534269
580
65328
S411
A
N
N
P
Q
A
I
S
Q
Q
D
L
V
H
M
Cat
Felis silvestris
Mouse
Mus musculus
Q01887
594
66266
S425
A
N
N
P
Q
A
I
S
Q
Q
D
L
V
H
M
Rat
Rattus norvegicus
P57097
994
109405
P691
E
S
V
P
K
S
I
P
L
Q
T
L
L
K
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422674
661
73662
S492
A
N
N
P
Q
A
I
S
Q
Q
D
L
V
H
M
Frog
Xenopus laevis
Q8QFP9
880
97916
P613
G
E
E
P
I
T
L
P
V
Q
T
L
V
R
F
Zebra Danio
Brachydanio rerio
Q9YI66
874
97580
S607
G
D
E
P
F
T
V
S
Q
Q
I
L
I
Q
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V422
584
64919
T415
P
A
C
A
R
T
V
T
T
I
Q
I
V
M
M
Honey Bee
Apis mellifera
XP_393673
688
76914
T519
E
G
P
P
R
A
L
T
T
Q
E
V
V
E
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788381
522
58475
I362
R
D
L
V
H
L
A
I
Q
I
T
H
G
M
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
74.5
89
N.A.
93
23.2
N.A.
N.A.
80.4
23.1
22
N.A.
36.2
31.8
N.A.
41.7
Protein Similarity:
100
N.A.
76.2
91.2
N.A.
94.5
35.7
N.A.
N.A.
85
38
37.4
N.A.
56.1
49.5
N.A.
58.7
P-Site Identity:
100
N.A.
100
100
N.A.
100
26.6
N.A.
N.A.
100
26.6
33.3
N.A.
13.3
33.3
N.A.
13.3
P-Site Similarity:
100
N.A.
100
100
N.A.
100
53.3
N.A.
N.A.
100
33.3
53.3
N.A.
40
66.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
46
10
0
10
0
55
10
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
19
0
0
0
0
0
0
0
0
46
0
0
0
0
% D
% Glu:
19
10
19
0
0
0
0
0
0
0
10
0
0
10
0
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
28
% F
% Gly:
19
10
0
0
0
0
0
0
0
0
0
0
10
0
0
% G
% His:
0
0
0
0
10
0
0
0
0
0
0
10
0
46
0
% H
% Ile:
0
0
0
0
10
0
55
10
0
19
10
10
10
0
0
% I
% Lys:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% K
% Leu:
0
0
10
0
0
10
19
0
10
0
0
73
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
19
73
% M
% Asn:
0
46
46
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
10
82
0
0
0
19
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
46
0
0
0
64
82
10
0
0
10
0
% Q
% Arg:
10
0
0
0
19
0
0
0
0
0
0
0
0
10
0
% R
% Ser:
0
10
0
0
0
10
0
55
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
28
0
19
19
0
28
0
0
0
0
% T
% Val:
0
0
10
10
0
0
19
0
10
0
0
10
73
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _