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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSPA1L
All Species:
33.64
Human Site:
S565
Identified Species:
67.27
UniProt:
P34931
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P34931
NP_005518.3
641
70375
S565
E
G
L
K
G
K
I
S
E
S
D
K
N
K
I
Chimpanzee
Pan troglodytes
XP_527345
641
70451
S565
E
G
L
K
G
K
I
S
E
S
D
K
N
K
I
Rhesus Macaque
Macaca mulatta
XP_001113329
641
70349
S565
E
G
L
K
G
K
I
S
E
S
D
K
K
K
I
Dog
Lupus familis
XP_532082
641
70502
N565
E
G
L
K
G
K
I
N
D
S
D
K
K
K
I
Cat
Felis silvestris
Mouse
Mus musculus
P16627
641
70619
S565
E
G
L
K
D
K
I
S
E
S
D
K
K
K
I
Rat
Rattus norvegicus
P55063
641
70531
S565
E
G
L
K
D
K
I
S
E
S
D
K
K
K
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510204
645
70485
S567
G
G
L
R
G
K
I
S
E
G
D
R
Q
K
V
Chicken
Gallus gallus
O73885
646
70808
L563
E
K
L
P
G
K
I
L
D
E
D
H
Q
N
I
Frog
Xenopus laevis
P02827
647
70897
S564
E
N
V
K
G
K
I
S
D
E
D
K
R
T
I
Zebra Danio
Brachydanio rerio
Q90473
649
70955
S563
E
K
L
K
G
K
I
S
D
E
D
K
Q
K
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P11147
651
71113
S563
D
N
L
K
T
K
I
S
D
S
D
R
T
T
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P09446
640
69704
S564
E
K
L
K
D
K
I
S
P
E
D
K
K
K
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
98.5
96
N.A.
94.6
94.5
N.A.
87.1
82.1
83.1
82.2
N.A.
80
N.A.
80.9
N.A.
Protein Similarity:
100
99.6
99
98.1
N.A.
96.2
96.2
N.A.
94.1
91.3
93
90.5
N.A.
89
N.A.
89.8
N.A.
P-Site Identity:
100
100
93.3
80
N.A.
86.6
86.6
N.A.
60
46.6
60
73.3
N.A.
53.3
N.A.
66.6
N.A.
P-Site Similarity:
100
100
93.3
93.3
N.A.
86.6
86.6
N.A.
80
53.3
73.3
80
N.A.
73.3
N.A.
66.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
25
0
0
0
42
0
100
0
0
0
0
% D
% Glu:
84
0
0
0
0
0
0
0
50
34
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
59
0
0
67
0
0
0
0
9
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% H
% Ile:
0
0
0
0
0
0
100
0
0
0
0
0
0
0
92
% I
% Lys:
0
25
0
84
0
100
0
0
0
0
0
75
42
75
0
% K
% Leu:
0
0
92
0
0
0
0
9
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
17
0
0
0
0
0
9
0
0
0
0
17
9
0
% N
% Pro:
0
0
0
9
0
0
0
0
9
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
25
0
0
% Q
% Arg:
0
0
0
9
0
0
0
0
0
0
0
17
9
0
0
% R
% Ser:
0
0
0
0
0
0
0
84
0
59
0
0
0
0
0
% S
% Thr:
0
0
0
0
9
0
0
0
0
0
0
0
9
17
0
% T
% Val:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _