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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSPA4
All Species:
29.7
Human Site:
S546
Identified Species:
50.26
UniProt:
P34932
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P34932
NP_002145.3
840
94331
S546
P
A
E
N
K
A
E
S
E
E
M
E
T
S
Q
Chimpanzee
Pan troglodytes
XP_517930
840
94350
S546
P
A
E
N
K
A
E
S
E
E
M
E
T
S
Q
Rhesus Macaque
Macaca mulatta
XP_001106968
840
94362
S546
P
A
E
N
K
A
E
S
E
E
M
E
T
S
Q
Dog
Lupus familis
XP_533297
840
94621
T546
Q
K
C
H
A
E
H
T
P
E
E
E
I
D
H
Cat
Felis silvestris
Mouse
Mus musculus
Q61316
841
94114
S548
P
A
E
N
K
A
E
S
E
E
M
E
T
S
Q
Rat
Rattus norvegicus
O88600
840
94038
S546
P
A
E
N
K
A
E
S
E
E
M
E
T
S
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510127
834
93982
S540
P
T
E
N
K
V
E
S
E
E
M
E
T
S
Q
Chicken
Gallus gallus
XP_414655
840
94222
S546
Q
A
E
N
K
A
E
S
E
E
M
E
T
S
Q
Frog
Xenopus laevis
P02827
647
70897
M411
L
E
T
A
G
G
V
M
T
V
L
I
K
R
N
Zebra Danio
Brachydanio rerio
NP_956151
840
94728
E548
G
E
K
K
P
G
T
E
E
M
E
T
S
A
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q05036
776
86878
V537
P
V
K
K
T
K
L
V
P
V
D
L
E
V
I
Sea Urchin
Strong. purpuratus
Q06068
889
98600
D566
G
S
K
E
T
S
K
D
S
K
D
Q
T
S
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32590
693
77602
S456
S
K
L
P
K
G
T
S
T
T
I
A
K
W
S
Red Bread Mold
Neurospora crassa
O74225
707
78655
T471
S
I
K
G
V
H
A
T
E
G
P
E
D
F
M
Conservation
Percent
Protein Identity:
100
99.7
99.5
63.9
N.A.
95.8
95.8
N.A.
87
85.9
27.8
73.2
N.A.
N.A.
N.A.
42
50.2
Protein Similarity:
100
99.7
99.7
79.6
N.A.
97.8
98.2
N.A.
92.3
93.2
46.1
85.8
N.A.
N.A.
N.A.
59.1
67.2
P-Site Identity:
100
100
100
13.3
N.A.
100
100
N.A.
86.6
93.3
0
6.6
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
100
100
100
26.6
N.A.
100
100
N.A.
86.6
93.3
6.6
33.3
N.A.
N.A.
N.A.
13.3
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
34.5
38.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51.5
55
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
43
0
8
8
43
8
0
0
0
0
8
0
8
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
0
0
15
0
8
8
0
% D
% Glu:
0
15
50
8
0
8
50
8
65
58
15
65
8
0
15
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
15
0
0
8
8
22
0
0
0
8
0
0
0
0
0
% G
% His:
0
0
0
8
0
8
8
0
0
0
0
0
0
0
8
% H
% Ile:
0
8
0
0
0
0
0
0
0
0
8
8
8
0
8
% I
% Lys:
0
15
29
15
58
8
8
0
0
8
0
0
15
0
0
% K
% Leu:
8
0
8
0
0
0
8
0
0
0
8
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
8
0
8
50
0
0
0
8
% M
% Asn:
0
0
0
50
0
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
50
0
0
8
8
0
0
0
15
0
8
0
0
0
0
% P
% Gln:
15
0
0
0
0
0
0
0
0
0
0
8
0
0
50
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% R
% Ser:
15
8
0
0
0
8
0
58
8
0
0
0
8
58
8
% S
% Thr:
0
8
8
0
15
0
15
15
15
8
0
8
58
0
0
% T
% Val:
0
8
0
0
8
8
8
8
0
15
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _