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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HSPA4 All Species: 18.18
Human Site: S830 Identified Species: 30.77
UniProt: P34932 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P34932 NP_002145.3 840 94331 S830 D T A V P S D S D K K L P E M
Chimpanzee Pan troglodytes XP_517930 840 94350 S830 D T A V P S D S D K K L P E M
Rhesus Macaque Macaca mulatta XP_001106968 840 94362 S830 D T A V P S E S D K K L P E M
Dog Lupus familis XP_533297 840 94621 S833 D S S Q H T K S S G E M E V D
Cat Felis silvestris
Mouse Mus musculus Q61316 841 94114 G831 D T A V P S D G D K K L P E M
Rat Rattus norvegicus O88600 840 94038 G830 D T A V P S D G D K K L P E M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510127 834 93982 S824 N S T A P A D S E K K L P E M
Chicken Gallus gallus XP_414655 840 94222 A830 T A P A P A A A E K K L P E M
Frog Xenopus laevis P02827 647 70897 G640 A R Q G G N S G P T I E E V D
Zebra Danio Brachydanio rerio NP_956151 840 94728 A828 E P A A A D S A G N T E N K P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q05036 776 86878 S768 A A G D Q P Q S Q P G E M D V
Sea Urchin Strong. purpuratus Q06068 889 98600 T866 D T S D Q A P T G E A S K E G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32590 693 77602 N686 S D D S D D N N D E N M D L D
Red Bread Mold Neurospora crassa O74225 707 78655 P700 E M T D A D A P K P V V E E A
Conservation
Percent
Protein Identity: 100 99.7 99.5 63.9 N.A. 95.8 95.8 N.A. 87 85.9 27.8 73.2 N.A. N.A. N.A. 42 50.2
Protein Similarity: 100 99.7 99.7 79.6 N.A. 97.8 98.2 N.A. 92.3 93.2 46.1 85.8 N.A. N.A. N.A. 59.1 67.2
P-Site Identity: 100 100 93.3 13.3 N.A. 93.3 93.3 N.A. 60 46.6 0 6.6 N.A. N.A. N.A. 6.6 20
P-Site Similarity: 100 100 100 46.6 N.A. 93.3 93.3 N.A. 86.6 66.6 6.6 26.6 N.A. N.A. N.A. 20 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 34.5 38.4
Protein Similarity: N.A. N.A. N.A. N.A. 51.5 55
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 15 43 22 15 22 15 15 0 0 8 0 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 50 8 8 22 8 22 36 0 43 0 0 0 8 8 22 % D
% Glu: 15 0 0 0 0 0 8 0 15 15 8 22 22 65 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 8 8 8 0 0 22 15 8 8 0 0 0 8 % G
% His: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 8 0 8 50 50 0 8 8 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 50 0 8 0 % L
% Met: 0 8 0 0 0 0 0 0 0 0 0 15 8 0 50 % M
% Asn: 8 0 0 0 0 8 8 8 0 8 8 0 8 0 0 % N
% Pro: 0 8 8 0 50 8 8 8 8 15 0 0 50 0 8 % P
% Gln: 0 0 8 8 15 0 8 0 8 0 0 0 0 0 0 % Q
% Arg: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 8 15 15 8 0 36 15 43 8 0 0 8 0 0 0 % S
% Thr: 8 43 15 0 0 8 0 8 0 8 8 0 0 0 0 % T
% Val: 0 0 0 36 0 0 0 0 0 0 8 8 0 15 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _