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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HSPA4 All Species: 31.21
Human Site: T113 Identified Species: 52.82
UniProt: P34932 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P34932 NP_002145.3 840 94331 T113 M E E E R N F T T E Q V T A M
Chimpanzee Pan troglodytes XP_517930 840 94350 T113 M E E E R N F T T E Q V T A M
Rhesus Macaque Macaca mulatta XP_001106968 840 94362 T113 M E E E R N F T T E Q V T A M
Dog Lupus familis XP_533297 840 94621 A113 L E E E R P F A I E Q V T G M
Cat Felis silvestris
Mouse Mus musculus Q61316 841 94114 T113 M E E E R N F T T E Q V T A M
Rat Rattus norvegicus O88600 840 94038 T113 M E E E R N F T T E Q V T A M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510127 834 93982 G113 F T T E Q V T G M L L S K L K
Chicken Gallus gallus XP_414655 840 94222 T113 M E E E R N F T I E Q M T G M
Frog Xenopus laevis P02827 647 70897 D11 K G V A V G I D L G T T Y S C
Zebra Danio Brachydanio rerio NP_956151 840 94728 S113 M E E E K V F S I E Q V T A M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q05036 776 86878 T113 L G E P H T F T P E Q V L A A
Sea Urchin Strong. purpuratus Q06068 889 98600 T113 L G E T E T F T P E Q I Y A M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32590 693 77602 K56 L G E S G K T K Q T S N V K N
Red Bread Mold Neurospora crassa O74225 707 78655 A71 V G C L K R L A G R T L D D P
Conservation
Percent
Protein Identity: 100 99.7 99.5 63.9 N.A. 95.8 95.8 N.A. 87 85.9 27.8 73.2 N.A. N.A. N.A. 42 50.2
Protein Similarity: 100 99.7 99.7 79.6 N.A. 97.8 98.2 N.A. 92.3 93.2 46.1 85.8 N.A. N.A. N.A. 59.1 67.2
P-Site Identity: 100 100 100 66.6 N.A. 100 100 N.A. 6.6 80 0 73.3 N.A. N.A. N.A. 46.6 46.6
P-Site Similarity: 100 100 100 73.3 N.A. 100 100 N.A. 13.3 86.6 6.6 86.6 N.A. N.A. N.A. 53.3 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. 34.5 38.4
Protein Similarity: N.A. N.A. N.A. N.A. 51.5 55
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 0
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 0 0 15 0 0 0 0 0 58 8 % A
% Cys: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 8 % C
% Asp: 0 0 0 0 0 0 0 8 0 0 0 0 8 8 0 % D
% Glu: 0 58 79 65 8 0 0 0 0 72 0 0 0 0 0 % E
% Phe: 8 0 0 0 0 0 72 0 0 0 0 0 0 0 0 % F
% Gly: 0 36 0 0 8 8 0 8 8 8 0 0 0 15 0 % G
% His: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 8 0 22 0 0 8 0 0 0 % I
% Lys: 8 0 0 0 15 8 0 8 0 0 0 0 8 8 8 % K
% Leu: 29 0 0 8 0 0 8 0 8 8 8 8 8 8 0 % L
% Met: 50 0 0 0 0 0 0 0 8 0 0 8 0 0 65 % M
% Asn: 0 0 0 0 0 43 0 0 0 0 0 8 0 0 8 % N
% Pro: 0 0 0 8 0 8 0 0 15 0 0 0 0 0 8 % P
% Gln: 0 0 0 0 8 0 0 0 8 0 72 0 0 0 0 % Q
% Arg: 0 0 0 0 50 8 0 0 0 8 0 0 0 0 0 % R
% Ser: 0 0 0 8 0 0 0 8 0 0 8 8 0 8 0 % S
% Thr: 0 8 8 8 0 15 15 58 36 8 15 8 58 0 0 % T
% Val: 8 0 8 0 8 15 0 0 0 0 0 58 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 15 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _