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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HSPA4 All Species: 31.82
Human Site: Y89 Identified Species: 53.85
UniProt: P34932 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P34932 NP_002145.3 840 94331 Y89 A E K S N L A Y D I V Q L P T
Chimpanzee Pan troglodytes XP_517930 840 94350 Y89 A E K S N L A Y D I V Q L P T
Rhesus Macaque Macaca mulatta XP_001106968 840 94362 Y89 A E K S N L A Y D I V Q L P T
Dog Lupus familis XP_533297 840 94621 Y89 T E R I R L P Y E L Q K M P N
Cat Felis silvestris
Mouse Mus musculus Q61316 841 94114 Y89 A E K S N L A Y D I V Q L P T
Rat Rattus norvegicus O88600 840 94038 Y89 A E K S N L A Y D I V Q L P T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510127 834 93982 P89 A Y E V V Q L P T G S A G I K
Chicken Gallus gallus XP_414655 840 94222 Y89 A E K T S L A Y E L V Q L P T
Frog Xenopus laevis P02827 647 70897
Zebra Danio Brachydanio rerio NP_956151 840 94728 Y89 N L K P S L V Y D L A Q M P S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q05036 776 86878 C89 R F I P F I P C K V V K L P N
Sea Urchin Strong. purpuratus Q06068 889 98600 Y89 K D A K V V P Y K I T Q L P N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32590 693 77602 S32 D V V V N E V S N R S T P S L
Red Bread Mold Neurospora crassa O74225 707 78655 Y47 G F G P K S R Y I G E P A K T
Conservation
Percent
Protein Identity: 100 99.7 99.5 63.9 N.A. 95.8 95.8 N.A. 87 85.9 27.8 73.2 N.A. N.A. N.A. 42 50.2
Protein Similarity: 100 99.7 99.7 79.6 N.A. 97.8 98.2 N.A. 92.3 93.2 46.1 85.8 N.A. N.A. N.A. 59.1 67.2
P-Site Identity: 100 100 100 26.6 N.A. 100 100 N.A. 6.6 73.3 0 40 N.A. N.A. N.A. 20 33.3
P-Site Similarity: 100 100 100 60 N.A. 100 100 N.A. 13.3 100 0 66.6 N.A. N.A. N.A. 40 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 34.5 38.4
Protein Similarity: N.A. N.A. N.A. N.A. 51.5 55
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 50 0 8 0 0 0 43 0 0 0 8 8 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % C
% Asp: 8 8 0 0 0 0 0 0 43 0 0 0 0 0 0 % D
% Glu: 0 50 8 0 0 8 0 0 15 0 8 0 0 0 0 % E
% Phe: 0 15 0 0 8 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 8 0 0 0 0 0 0 15 0 0 8 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 8 8 0 8 0 0 8 43 0 0 0 8 0 % I
% Lys: 8 0 50 8 8 0 0 0 15 0 0 15 0 8 8 % K
% Leu: 0 8 0 0 0 58 8 0 0 22 0 0 58 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 15 0 0 % M
% Asn: 8 0 0 0 43 0 0 0 8 0 0 0 0 0 22 % N
% Pro: 0 0 0 22 0 0 22 8 0 0 0 8 8 72 0 % P
% Gln: 0 0 0 0 0 8 0 0 0 0 8 58 0 0 0 % Q
% Arg: 8 0 8 0 8 0 8 0 0 8 0 0 0 0 0 % R
% Ser: 0 0 0 36 15 8 0 8 0 0 15 0 0 8 8 % S
% Thr: 8 0 0 8 0 0 0 0 8 0 8 8 0 0 50 % T
% Val: 0 8 8 15 15 8 15 0 0 8 50 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 72 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _