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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRK5
All Species:
36.36
Human Site:
S413
Identified Species:
72.73
UniProt:
P34947
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P34947
NP_005299.1
590
67787
S413
E
V
Y
S
H
K
F
S
E
E
A
K
S
I
C
Chimpanzee
Pan troglodytes
XP_527138
582
66476
S406
E
E
Y
S
E
R
F
S
P
Q
A
R
S
L
C
Rhesus Macaque
Macaca mulatta
XP_001090237
589
67275
S413
E
E
Y
S
E
R
F
S
P
Q
A
R
S
L
C
Dog
Lupus familis
XP_544045
601
68781
S424
E
T
Y
S
Q
K
F
S
E
E
A
K
S
I
C
Cat
Felis silvestris
Mouse
Mus musculus
Q8VEB1
590
67714
S413
E
V
Y
S
S
K
F
S
E
E
A
K
S
I
C
Rat
Rattus norvegicus
Q62833
590
67764
S413
E
V
Y
S
P
K
F
S
E
E
A
K
S
I
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514774
604
69204
S427
E
V
Y
S
H
K
F
S
E
E
A
K
S
V
C
Chicken
Gallus gallus
XP_421789
590
67665
S413
E
V
Y
S
H
K
F
S
E
E
A
K
S
I
C
Frog
Xenopus laevis
Q6IP76
485
56005
D358
R
L
P
F
Y
N
Q
D
H
E
R
L
F
E
L
Zebra Danio
Brachydanio rerio
XP_689783
575
66134
S413
E
E
Y
S
S
K
F
S
E
D
A
K
S
L
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P32866
714
80668
N537
E
K
Y
S
S
K
F
N
D
E
A
K
S
M
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09537
642
73759
S430
E
K
Y
S
E
K
F
S
E
A
A
R
T
L
C
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.4
69.4
93
N.A.
95.2
95
N.A.
82.2
91
30
71.3
N.A.
53.6
N.A.
53.2
N.A.
Protein Similarity:
100
80.1
82.1
96
N.A.
97.4
97.4
N.A.
87.9
95.2
44.9
83.3
N.A.
65.1
N.A.
68.5
N.A.
P-Site Identity:
100
53.3
53.3
86.6
N.A.
93.3
93.3
N.A.
93.3
100
6.6
73.3
N.A.
66.6
N.A.
60
N.A.
P-Site Similarity:
100
80
80
86.6
N.A.
93.3
93.3
N.A.
100
100
20
86.6
N.A.
86.6
N.A.
80
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
9
92
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
92
% C
% Asp:
0
0
0
0
0
0
0
9
9
9
0
0
0
0
0
% D
% Glu:
92
25
0
0
25
0
0
0
67
67
0
0
0
9
0
% E
% Phe:
0
0
0
9
0
0
92
0
0
0
0
0
9
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
25
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
42
0
% I
% Lys:
0
17
0
0
0
75
0
0
0
0
0
67
0
0
0
% K
% Leu:
0
9
0
0
0
0
0
0
0
0
0
9
0
34
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
0
0
0
0
0
9
0
9
0
0
0
0
0
0
0
% N
% Pro:
0
0
9
0
9
0
0
0
17
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
9
0
9
0
0
17
0
0
0
0
0
% Q
% Arg:
9
0
0
0
0
17
0
0
0
0
9
25
0
0
0
% R
% Ser:
0
0
0
92
25
0
0
84
0
0
0
0
84
0
0
% S
% Thr:
0
9
0
0
0
0
0
0
0
0
0
0
9
0
0
% T
% Val:
0
42
0
0
0
0
0
0
0
0
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
92
0
9
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _