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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MPI All Species: 19.7
Human Site: S355 Identified Species: 36.11
UniProt: P34949 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P34949 NP_002426.1 423 46656 S355 M K T E V P G S V T E Y K V L
Chimpanzee Pan troglodytes A5A6K3 423 46593 S355 M K T E V P G S V T G Y K V L
Rhesus Macaque Macaca mulatta XP_001098369 246 27237 S187 K Q T M S H D S Q A V A S A L
Dog Lupus familis XP_535543 421 46205 S353 M K M Q V P G S V A E Y N V L
Cat Felis silvestris
Mouse Mus musculus Q924M7 423 46556 S355 M K M E V P S S V T E Y K V S
Rat Rattus norvegicus Q68FX1 423 46405 S355 M K I E V P G S V T E Y K V L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511999 423 46243 S355 M K I E V P A S A K P Y T V S
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623842 403 45248 A341 I T I P P G R A S Y N I I P R
Nematode Worm Caenorhab. elegans P34650 416 46365 Y338 K G P A G S I Y Q L P Y S E S
Sea Urchin Strong. purpuratus XP_780304 431 46368 D360 A R V K V P A D Q A S Y T L R
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001140476 435 47737 V367 V P P G G S L V V V P P V P G
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P29952 429 48170 F360 F A V L E T T F D E K L G Q R
Red Bread Mold Neurospora crassa Q870Y1 459 50345 V368 I D S Q S E I V E Y N P P I E
Conservation
Percent
Protein Identity: 100 99.5 55.7 88.4 N.A. 84.6 85.5 N.A. 73.2 N.A. N.A. N.A. N.A. N.A. 44.4 39.7 48.7
Protein Similarity: 100 99.7 56.9 93.3 N.A. 91.2 91 N.A. 81.8 N.A. N.A. N.A. N.A. N.A. 61.7 58.3 66.3
P-Site Identity: 100 93.3 20 73.3 N.A. 80 93.3 N.A. 53.3 N.A. N.A. N.A. N.A. N.A. 0 6.6 20
P-Site Similarity: 100 93.3 26.6 80 N.A. 80 93.3 N.A. 53.3 N.A. N.A. N.A. N.A. N.A. 13.3 6.6 40
Percent
Protein Identity: N.A. 40.9 N.A. N.A. 40.7 38.1
Protein Similarity: N.A. 55.8 N.A. N.A. 59.9 54.6
P-Site Identity: N.A. 6.6 N.A. N.A. 0 0
P-Site Similarity: N.A. 13.3 N.A. N.A. 6.6 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 8 0 0 16 8 8 24 0 8 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 0 8 8 8 0 0 0 0 0 0 % D
% Glu: 0 0 0 39 8 8 0 0 8 8 31 0 0 8 8 % E
% Phe: 8 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % F
% Gly: 0 8 0 8 16 8 31 0 0 0 8 0 8 0 8 % G
% His: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % H
% Ile: 16 0 24 0 0 0 16 0 0 0 0 8 8 8 0 % I
% Lys: 16 47 0 8 0 0 0 0 0 8 8 0 31 0 0 % K
% Leu: 0 0 0 8 0 0 8 0 0 8 0 8 0 8 39 % L
% Met: 47 0 16 8 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 16 0 8 0 0 % N
% Pro: 0 8 16 8 8 54 0 0 0 0 24 16 8 16 0 % P
% Gln: 0 8 0 16 0 0 0 0 24 0 0 0 0 8 0 % Q
% Arg: 0 8 0 0 0 0 8 0 0 0 0 0 0 0 24 % R
% Ser: 0 0 8 0 16 16 8 54 8 0 8 0 16 0 24 % S
% Thr: 0 8 24 0 0 8 8 0 0 31 0 0 16 0 0 % T
% Val: 8 0 16 0 54 0 0 16 47 8 8 0 8 47 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 8 0 16 0 62 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _