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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MPI
All Species:
19.7
Human Site:
T409
Identified Species:
36.11
UniProt:
P34949
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P34949
NP_002426.1
423
46656
T409
E
S
V
S
L
K
L
T
E
P
K
D
L
L
I
Chimpanzee
Pan troglodytes
A5A6K3
423
46593
T409
E
S
V
S
L
K
L
T
E
P
K
D
L
L
I
Rhesus Macaque
Macaca mulatta
XP_001098369
246
27237
G239
W
V
Q
C
S
D
L
G
S
P
A
D
T
R
L
Dog
Lupus familis
XP_535543
421
46205
A407
E
R
V
S
L
K
L
A
V
P
S
D
L
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q924M7
423
46556
T409
E
S
V
L
L
K
I
T
V
P
K
D
L
L
I
Rat
Rattus norvegicus
Q68FX1
423
46405
T409
E
T
V
L
L
K
L
T
V
P
K
N
L
L
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511999
423
46243
T409
E
S
V
S
L
Q
L
T
S
S
G
S
L
L
M
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623842
403
45248
M396
C
G
C
H
P
M
L
M
F
Q
A
F
V
N
V
Nematode Worm
Caenorhab. elegans
P34650
416
46365
F398
D
F
L
A
F
R
A
F
T
P
S
P
R
A
L
Sea Urchin
Strong. purpuratus
XP_780304
431
46368
S416
E
S
L
A
F
K
L
S
P
A
N
G
L
L
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001140476
435
47737
Y425
G
P
E
S
L
Q
L
Y
R
A
G
V
N
S
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P29952
429
48170
E415
L
P
V
D
L
E
A
E
D
E
A
F
T
T
Y
Red Bread Mold
Neurospora crassa
Q870Y1
459
50345
E439
A
E
C
V
L
E
S
E
D
D
K
F
E
T
F
Conservation
Percent
Protein Identity:
100
99.5
55.7
88.4
N.A.
84.6
85.5
N.A.
73.2
N.A.
N.A.
N.A.
N.A.
N.A.
44.4
39.7
48.7
Protein Similarity:
100
99.7
56.9
93.3
N.A.
91.2
91
N.A.
81.8
N.A.
N.A.
N.A.
N.A.
N.A.
61.7
58.3
66.3
P-Site Identity:
100
100
20
66.6
N.A.
80
73.3
N.A.
60
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
6.6
40
P-Site Similarity:
100
100
26.6
73.3
N.A.
86.6
86.6
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
20
40
60
Percent
Protein Identity:
N.A.
40.9
N.A.
N.A.
40.7
38.1
Protein Similarity:
N.A.
55.8
N.A.
N.A.
59.9
54.6
P-Site Identity:
N.A.
20
N.A.
N.A.
13.3
13.3
P-Site Similarity:
N.A.
26.6
N.A.
N.A.
26.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
16
0
0
16
8
0
16
24
0
0
8
8
% A
% Cys:
8
0
16
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
8
0
8
0
0
16
8
0
39
0
0
0
% D
% Glu:
54
8
8
0
0
16
0
16
16
8
0
0
8
0
0
% E
% Phe:
0
8
0
0
16
0
0
8
8
0
0
24
0
0
8
% F
% Gly:
8
8
0
0
0
0
0
8
0
0
16
8
0
0
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
31
% I
% Lys:
0
0
0
0
0
47
0
0
0
0
39
0
0
0
0
% K
% Leu:
8
0
16
16
70
0
70
0
0
0
0
0
54
54
24
% L
% Met:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
8
8
8
0
% N
% Pro:
0
16
0
0
8
0
0
0
8
54
0
8
0
0
0
% P
% Gln:
0
0
8
0
0
16
0
0
0
8
0
0
0
0
0
% Q
% Arg:
0
8
0
0
0
8
0
0
8
0
0
0
8
8
8
% R
% Ser:
0
39
0
39
8
0
8
8
16
8
16
8
0
8
0
% S
% Thr:
0
8
0
0
0
0
0
39
8
0
0
0
16
16
0
% T
% Val:
0
8
54
8
0
0
0
0
24
0
0
8
8
0
8
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _