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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HTR7
All Species:
0
Human Site:
S269
Identified Species:
0
UniProt:
P34969
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P34969
NP_000863.1
479
53555
S269
I
Y
K
A
A
R
K
S
A
A
K
H
K
F
P
Chimpanzee
Pan troglodytes
Q9N2D9
365
41472
I174
S
R
D
D
E
C
I
I
K
H
B
H
I
V
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534958
448
49654
M257
F
Y
I
P
M
S
V
M
L
F
M
Y
Y
Q
I
Cat
Felis silvestris
Mouse
Mus musculus
P32304
448
49843
V257
A
F
Y
I
P
M
S
V
M
L
F
M
Y
Y
Q
Rat
Rattus norvegicus
P32305
448
49818
V257
A
F
Y
I
P
M
S
V
M
L
F
M
Y
Y
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505726
203
23454
L12
A
V
A
F
Y
I
P
L
S
E
M
L
F
M
Y
Chicken
Gallus gallus
NP_001167605
425
47022
G234
C
L
I
S
Q
D
F
G
Y
T
I
Y
S
T
A
Frog
Xenopus laevis
Q91559
425
47998
A234
G
Y
T
V
Y
S
T
A
V
A
F
Y
I
P
M
Zebra Danio
Brachydanio rerio
XP_690599
396
44340
A205
M
Y
Y
R
I
F
R
A
A
K
L
S
A
A
K
Tiger Blowfish
Takifugu rubipres
O42385
423
46982
R232
G
R
I
F
K
A
A
R
F
R
I
R
K
T
V
Fruit Fly
Dros. melanogaster
P20905
564
60843
I352
I
F
R
A
A
R
R
I
V
L
E
E
K
R
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786251
486
54084
I274
A
A
D
R
S
G
S
I
S
S
E
S
D
S
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
25.2
N.A.
87.6
N.A.
86.6
88.3
N.A.
32.9
72.4
58.6
64
26.7
26.6
N.A.
N.A.
35.1
Protein Similarity:
100
41.5
N.A.
89.9
N.A.
88.5
89.5
N.A.
37.7
78
68.6
72
43.2
42.2
N.A.
N.A.
50.4
P-Site Identity:
100
6.6
N.A.
6.6
N.A.
0
0
N.A.
0
0
13.3
13.3
6.6
33.3
N.A.
N.A.
0
P-Site Similarity:
100
6.6
N.A.
13.3
N.A.
13.3
13.3
N.A.
6.6
13.3
26.6
33.3
6.6
60
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
9
9
17
17
9
9
17
17
17
0
0
9
9
17
% A
% Cys:
9
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
17
9
0
9
0
0
0
0
0
0
9
0
0
% D
% Glu:
0
0
0
0
9
0
0
0
0
9
17
9
0
0
0
% E
% Phe:
9
25
0
17
0
9
9
0
9
9
25
0
9
9
0
% F
% Gly:
17
0
0
0
0
9
0
9
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
17
0
0
0
% H
% Ile:
17
0
25
17
9
9
9
25
0
0
17
0
17
0
9
% I
% Lys:
0
0
9
0
9
0
9
0
9
9
9
0
25
0
9
% K
% Leu:
0
9
0
0
0
0
0
9
9
25
9
9
0
0
0
% L
% Met:
9
0
0
0
9
17
0
9
17
0
17
17
0
9
9
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
9
17
0
9
0
0
0
0
0
0
9
9
% P
% Gln:
0
0
0
0
9
0
0
0
0
0
0
0
0
9
17
% Q
% Arg:
0
17
9
17
0
17
17
9
0
9
0
9
0
9
0
% R
% Ser:
9
0
0
9
9
17
25
9
17
9
0
17
9
9
9
% S
% Thr:
0
0
9
0
0
0
9
0
0
9
0
0
0
17
9
% T
% Val:
0
9
0
9
0
0
9
17
17
0
0
0
0
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
34
25
0
17
0
0
0
9
0
0
25
25
17
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _