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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HTR7 All Species: 0.3
Human Site: T189 Identified Species: 0.61
UniProt: P34969 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P34969 NP_000863.1 479 53555 T189 L G I T R P L T Y P V R Q N G
Chimpanzee Pan troglodytes Q9N2D9 365 41472 W99 G Q V V C D I W L S V D I T C
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_534958 448 49654 R182 L C V I S I D R Y L G I T R P
Cat Felis silvestris
Mouse Mus musculus P32304 448 49843 I181 M T L C V I S I D R Y L G I T
Rat Rattus norvegicus P32305 448 49818 D182 T L C V I S I D R Y L G I T R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505726 203 23454
Chicken Gallus gallus NP_001167605 425 47022 V159 N V F I A M D V M C C T A S I
Frog Xenopus laevis Q91559 425 47998 I159 V M C C T A S I M T L C V I S
Zebra Danio Brachydanio rerio XP_690599 396 44340 Y130 G I T R P L T Y P V R Q N G W
Tiger Blowfish Takifugu rubipres O42385 423 46982 R157 P I D Y V N K R T P R R A A V
Fruit Fly Dros. melanogaster P20905 564 60843 E269 L A I T K P L E Y G V K R T P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786251 486 54084 I199 I S F S P L L I F E N E H F A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 25.2 N.A. 87.6 N.A. 86.6 88.3 N.A. 32.9 72.4 58.6 64 26.7 26.6 N.A. N.A. 35.1
Protein Similarity: 100 41.5 N.A. 89.9 N.A. 88.5 89.5 N.A. 37.7 78 68.6 72 43.2 42.2 N.A. N.A. 50.4
P-Site Identity: 100 6.6 N.A. 13.3 N.A. 0 0 N.A. 0 0 0 0 13.3 46.6 N.A. N.A. 6.6
P-Site Similarity: 100 20 N.A. 20 N.A. 13.3 13.3 N.A. 0 6.6 13.3 6.6 13.3 66.6 N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 9 9 0 0 0 0 0 0 17 9 9 % A
% Cys: 0 9 17 17 9 0 0 0 0 9 9 9 0 0 9 % C
% Asp: 0 0 9 0 0 9 17 9 9 0 0 9 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 9 0 9 0 9 0 0 0 % E
% Phe: 0 0 17 0 0 0 0 0 9 0 0 0 0 9 0 % F
% Gly: 17 9 0 0 0 0 0 0 0 9 9 9 9 9 9 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % H
% Ile: 9 17 17 17 9 17 17 25 0 0 0 9 17 17 9 % I
% Lys: 0 0 0 0 9 0 9 0 0 0 0 9 0 0 0 % K
% Leu: 25 9 9 0 0 17 25 0 9 9 17 9 0 0 0 % L
% Met: 9 9 0 0 0 9 0 0 17 0 0 0 0 0 0 % M
% Asn: 9 0 0 0 0 9 0 0 0 0 9 0 9 9 0 % N
% Pro: 9 0 0 0 17 17 0 0 9 17 0 0 0 0 17 % P
% Gln: 0 9 0 0 0 0 0 0 0 0 0 9 9 0 0 % Q
% Arg: 0 0 0 9 9 0 0 17 9 9 17 17 9 9 9 % R
% Ser: 0 9 0 9 9 9 17 0 0 9 0 0 0 9 9 % S
% Thr: 9 9 9 17 9 0 9 9 9 9 0 9 9 25 9 % T
% Val: 9 9 17 17 17 0 0 9 0 9 25 0 9 0 9 % V
% Trp: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 9 % W
% Tyr: 0 0 0 9 0 0 0 9 25 9 9 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _