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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CRHR1
All Species:
34.55
Human Site:
S333
Identified Species:
84.44
UniProt:
P34998
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P34998
NP_001138618.1
444
50719
S333
K
L
R
A
S
T
T
S
E
T
I
Q
Y
R
K
Chimpanzee
Pan troglodytes
XP_001138338
415
47735
S304
K
L
R
A
S
T
T
S
E
T
I
Q
Y
R
K
Rhesus Macaque
Macaca mulatta
Q76LL8
415
47765
S304
K
L
R
A
S
T
T
S
E
T
I
Q
Y
R
K
Dog
Lupus familis
XP_852965
415
47735
S304
K
L
R
A
S
T
T
S
E
T
I
Q
Y
R
K
Cat
Felis silvestris
Mouse
Mus musculus
P35347
415
47750
S304
K
L
R
A
S
T
T
S
E
T
I
Q
Y
R
K
Rat
Rattus norvegicus
P35353
415
47824
S304
K
L
R
A
S
T
T
S
E
T
I
Q
Y
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90812
420
48581
S309
K
L
R
A
S
T
T
S
E
T
I
Q
Y
R
K
Frog
Xenopus laevis
O42602
415
47768
S304
K
L
R
A
S
T
T
S
E
T
I
Q
Y
R
K
Zebra Danio
Brachydanio rerio
Q68EK2
470
54084
A334
K
L
K
V
T
H
Q
A
K
S
S
L
Y
M
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W4Y2
669
74467
S439
K
L
R
Q
S
Q
A
S
D
I
E
Q
T
R
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93
93
91.4
N.A.
91.2
90.7
N.A.
N.A.
82.4
75.2
24.6
N.A.
24
N.A.
N.A.
N.A.
Protein Similarity:
100
93.2
93
92.5
N.A.
92.1
91.8
N.A.
N.A.
88
84.4
41.9
N.A.
34
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
100
26.6
N.A.
53.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
100
60
N.A.
60
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
80
0
0
10
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
80
0
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
10
80
0
0
0
0
% I
% Lys:
100
0
10
0
0
0
0
0
10
0
0
0
0
0
100
% K
% Leu:
0
100
0
0
0
0
0
0
0
0
0
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
10
0
10
10
0
0
0
0
90
0
0
0
% Q
% Arg:
0
0
90
0
0
0
0
0
0
0
0
0
0
90
0
% R
% Ser:
0
0
0
0
90
0
0
90
0
10
10
0
0
0
0
% S
% Thr:
0
0
0
0
10
80
80
0
0
80
0
0
10
0
0
% T
% Val:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
90
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _