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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CRHR1 All Species: 0.91
Human Site: T297 Identified Species: 2.22
UniProt: P34998 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P34998 NP_001138618.1 444 50719 T297 G K R P G V Y T D Y I Y Q G P
Chimpanzee Pan troglodytes XP_001138338 415 47735 I277 Y I Y Q G P M I L V L L I N F
Rhesus Macaque Macaca mulatta Q76LL8 415 47765 I277 Y I Y Q G P M I L V L L I N F
Dog Lupus familis XP_852965 415 47735 I277 Y I Y Q G P M I L V L L I N F
Cat Felis silvestris
Mouse Mus musculus P35347 415 47750 I277 Y I Y Q G P M I L V L L I N F
Rat Rattus norvegicus P35353 415 47824 I277 Y I Y Q G P M I L V L L I N F
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90812 420 48581 I282 Y I Y Q G P M I L V L L I N F
Frog Xenopus laevis O42602 415 47768 I277 F I Y Q G P V I L V L L I N F
Zebra Danio Brachydanio rerio Q68EK2 470 54084 Y300 S S N T S L L Y I I H G P I C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W4Y2 669 74467 Y404 N Y N L T P Y Y W I L E G P R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93 93 91.4 N.A. 91.2 90.7 N.A. N.A. 82.4 75.2 24.6 N.A. 24 N.A. N.A. N.A.
Protein Similarity: 100 93.2 93 92.5 N.A. 92.1 91.8 N.A. N.A. 88 84.4 41.9 N.A. 34 N.A. N.A. N.A.
P-Site Identity: 100 6.6 6.6 6.6 N.A. 6.6 6.6 N.A. N.A. 6.6 6.6 0 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 13.3 13.3 13.3 N.A. 13.3 13.3 N.A. N.A. 13.3 13.3 6.6 N.A. 13.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % C
% Asp: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % E
% Phe: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 70 % F
% Gly: 10 0 0 0 80 0 0 0 0 0 0 10 10 10 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % H
% Ile: 0 70 0 0 0 0 0 70 10 20 10 0 70 10 0 % I
% Lys: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 10 0 10 10 0 70 0 80 70 0 0 0 % L
% Met: 0 0 0 0 0 0 60 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 20 0 0 0 0 0 0 0 0 0 0 70 0 % N
% Pro: 0 0 0 10 0 80 0 0 0 0 0 0 10 10 10 % P
% Gln: 0 0 0 70 0 0 0 0 0 0 0 0 10 0 0 % Q
% Arg: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 10 % R
% Ser: 10 10 0 0 10 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 10 10 0 0 10 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 10 10 0 0 70 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % W
% Tyr: 60 10 70 0 0 0 20 20 0 10 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _