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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CRHR1 All Species: 26.97
Human Site: Y73 Identified Species: 65.93
UniProt: P34998 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P34998 NP_001138618.1 444 50719 Y73 R P C P A F F Y G V R Y N T T
Chimpanzee Pan troglodytes XP_001138338 415 47735 Y73 R P C P A F F Y G V R Y N T T
Rhesus Macaque Macaca mulatta Q76LL8 415 47765 Y73 R P C P A F F Y G V R Y N T T
Dog Lupus familis XP_852965 415 47735 Y73 R P C P A Y F Y G V R Y N T T
Cat Felis silvestris
Mouse Mus musculus P35347 415 47750 Y73 R P C P A F F Y G V R Y N T T
Rat Rattus norvegicus P35353 415 47824 Y73 R P C P A F F Y G V R Y N T T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90812 420 48581 Y78 R P C P E Y F Y G V R Y N T T
Frog Xenopus laevis O42602 415 47768 H73 R P C P E Y F H G V Q Y N T T
Zebra Danio Brachydanio rerio Q68EK2 470 54084 R69 K D N S Q D R R G P V C N R T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W4Y2 669 74467 D102 M D A L P D S D T E Q V L G N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93 93 91.4 N.A. 91.2 90.7 N.A. N.A. 82.4 75.2 24.6 N.A. 24 N.A. N.A. N.A.
Protein Similarity: 100 93.2 93 92.5 N.A. 92.1 91.8 N.A. N.A. 88 84.4 41.9 N.A. 34 N.A. N.A. N.A.
P-Site Identity: 100 100 100 93.3 N.A. 100 100 N.A. N.A. 86.6 73.3 20 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 93.3 93.3 26.6 N.A. 6.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 60 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 80 0 0 0 0 0 0 0 0 10 0 0 0 % C
% Asp: 0 20 0 0 0 20 0 10 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 20 0 0 0 0 10 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 50 80 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 90 0 0 0 0 10 0 % G
% His: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 10 0 0 0 0 0 0 0 0 10 0 0 % L
% Met: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 10 0 0 0 0 0 0 0 0 0 90 0 10 % N
% Pro: 0 80 0 80 10 0 0 0 0 10 0 0 0 0 0 % P
% Gln: 0 0 0 0 10 0 0 0 0 0 20 0 0 0 0 % Q
% Arg: 80 0 0 0 0 0 10 10 0 0 70 0 0 10 0 % R
% Ser: 0 0 0 10 0 0 10 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 10 0 0 0 0 80 90 % T
% Val: 0 0 0 0 0 0 0 0 0 80 10 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 30 0 70 0 0 0 80 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _