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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRSS3 All Species: 13.64
Human Site: T188 Identified Species: 42.86
UniProt: P35030 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P35030 NP_002762.2 304 32529 T188 S T I S L P T T P P A A G T E
Chimpanzee Pan troglodytes XP_001155576 299 31662 P183 T I S L P T A P A A P K G G X
Rhesus Macaque Macaca mulatta XP_001087821 247 26702 A131 S T I S L P S A L A A A G T E
Dog Lupus familis XP_532744 246 26259 S131 S A I A L P K S C P A A G T Q
Cat Felis silvestris
Mouse Mus musculus P07146 246 26185 S131 A S V P L P S S C A P A G T Q
Rat Rattus norvegicus P00763 246 26209 S131 A T V A L P S S C A P A G T Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90629 248 26604 S133 Q P I A L P S S C A K A G T E
Frog Xenopus laevis P70059 244 26061 A129 Q S V P L P S A C A S A G T N
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 84.8 71.3 59.2 N.A. 60.5 62.8 N.A. N.A. 55.2 55.2 N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 85.5 77.6 69.4 N.A. 71.3 73 N.A. N.A. 67.1 68 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 73.3 60 N.A. 33.3 40 N.A. N.A. 46.6 33.3 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 13.3 80 80 N.A. 73.3 80 N.A. N.A. 66.6 60 N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 25 13 0 38 0 0 13 25 13 75 38 88 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 63 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 38 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 100 13 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 13 50 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 13 0 0 0 13 13 0 0 0 % K
% Leu: 0 0 0 13 88 0 0 0 13 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 % N
% Pro: 0 13 0 25 13 88 0 13 13 25 38 0 0 0 0 % P
% Gln: 25 0 0 0 0 0 0 0 0 0 0 0 0 0 38 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 38 25 13 25 0 0 63 50 0 0 13 0 0 0 0 % S
% Thr: 13 38 0 0 0 13 13 13 0 0 0 0 0 88 0 % T
% Val: 0 0 38 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _