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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BTC
All Species:
19.09
Human Site:
T160
Identified Species:
60
UniProt:
P35070
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35070
NP_001720.1
178
19746
T160
K
K
E
E
E
M
E
T
L
G
K
D
I
T
P
Chimpanzee
Pan troglodytes
XP_517223
178
19706
T160
K
K
E
E
E
M
E
T
L
D
K
D
I
T
P
Rhesus Macaque
Macaca mulatta
P55244
121
13164
R104
L
I
H
C
C
Q
V
R
K
H
C
E
W
C
R
Dog
Lupus familis
XP_539798
190
21395
T172
K
K
E
E
E
M
E
T
L
G
K
D
I
T
P
Cat
Felis silvestris
Mouse
Mus musculus
Q05928
177
19646
T159
K
K
E
E
K
M
E
T
L
D
K
D
K
T
P
Rat
Rattus norvegicus
P01134
159
16942
C137
E
W
C
R
A
L
V
C
R
H
E
K
P
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510889
431
46044
T411
R
K
Q
E
E
M
D
T
L
D
K
E
S
A
P
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038229
178
20321
T152
K
K
K
R
K
K
Q
T
I
D
E
D
D
K
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.7
24.7
72.6
N.A.
79.2
31.4
N.A.
29.4
N.A.
N.A.
37
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.3
37.6
81.5
N.A.
85.3
44.9
N.A.
34.7
N.A.
N.A.
59.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
0
100
N.A.
80
0
N.A.
53.3
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
6.6
100
N.A.
86.6
26.6
N.A.
80
N.A.
N.A.
60
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
13
0
0
0
0
0
0
0
0
13
13
% A
% Cys:
0
0
13
13
13
0
0
13
0
0
13
0
0
13
0
% C
% Asp:
0
0
0
0
0
0
13
0
0
50
0
63
13
0
0
% D
% Glu:
13
0
50
63
50
0
50
0
0
0
25
25
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
25
0
0
0
0
0
% G
% His:
0
0
13
0
0
0
0
0
0
25
0
0
0
0
13
% H
% Ile:
0
13
0
0
0
0
0
0
13
0
0
0
38
0
0
% I
% Lys:
63
75
13
0
25
13
0
0
13
0
63
13
13
13
0
% K
% Leu:
13
0
0
0
0
13
0
0
63
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
63
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
63
% P
% Gln:
0
0
13
0
0
13
13
0
0
0
0
0
0
0
0
% Q
% Arg:
13
0
0
25
0
0
0
13
13
0
0
0
0
0
13
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
13
13
0
% S
% Thr:
0
0
0
0
0
0
0
75
0
0
0
0
0
50
0
% T
% Val:
0
0
0
0
0
0
25
0
0
0
0
0
0
0
0
% V
% Trp:
0
13
0
0
0
0
0
0
0
0
0
0
13
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _