KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BTC
All Species:
13.94
Human Site:
T166
Identified Species:
43.81
UniProt:
P35070
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35070
NP_001720.1
178
19746
T166
E
T
L
G
K
D
I
T
P
I
N
E
D
I
E
Chimpanzee
Pan troglodytes
XP_517223
178
19706
T166
E
T
L
D
K
D
I
T
P
V
N
E
D
I
E
Rhesus Macaque
Macaca mulatta
P55244
121
13164
C110
V
R
K
H
C
E
W
C
R
A
L
I
C
R
H
Dog
Lupus familis
XP_539798
190
21395
T178
E
T
L
G
K
D
I
T
P
I
N
E
D
I
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q05928
177
19646
T165
E
T
L
D
K
D
K
T
P
I
S
E
D
I
Q
Rat
Rattus norvegicus
P01134
159
16942
S143
V
C
R
H
E
K
P
S
A
L
L
K
G
R
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510889
431
46044
A417
D
T
L
D
K
E
S
A
P
K
P
E
G
T
D
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038229
178
20321
K158
Q
T
I
D
E
D
D
K
H
T
P
L
N
A
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.7
24.7
72.6
N.A.
79.2
31.4
N.A.
29.4
N.A.
N.A.
37
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.3
37.6
81.5
N.A.
85.3
44.9
N.A.
34.7
N.A.
N.A.
59.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
86.6
0
93.3
N.A.
73.3
0
N.A.
33.3
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
6.6
100
N.A.
86.6
26.6
N.A.
53.3
N.A.
N.A.
40
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
13
13
13
0
0
0
13
0
% A
% Cys:
0
13
0
0
13
0
0
13
0
0
0
0
13
0
0
% C
% Asp:
13
0
0
50
0
63
13
0
0
0
0
0
50
0
13
% D
% Glu:
50
0
0
0
25
25
0
0
0
0
0
63
0
0
25
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
25
0
0
0
0
0
0
0
0
25
0
0
% G
% His:
0
0
0
25
0
0
0
0
13
0
0
0
0
0
25
% H
% Ile:
0
0
13
0
0
0
38
0
0
38
0
13
0
50
0
% I
% Lys:
0
0
13
0
63
13
13
13
0
13
0
13
0
0
0
% K
% Leu:
0
0
63
0
0
0
0
0
0
13
25
13
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
38
0
13
0
0
% N
% Pro:
0
0
0
0
0
0
13
0
63
0
25
0
0
0
0
% P
% Gln:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
25
% Q
% Arg:
0
13
13
0
0
0
0
0
13
0
0
0
0
25
0
% R
% Ser:
0
0
0
0
0
0
13
13
0
0
13
0
0
0
0
% S
% Thr:
0
75
0
0
0
0
0
50
0
13
0
0
0
13
13
% T
% Val:
25
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _