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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PFN2
All Species:
39.39
Human Site:
Y129
Identified Species:
78.79
UniProt:
P35080
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35080
NP_002619.1
140
15046
Y129
G
G
L
N
K
K
A
Y
S
M
A
K
Y
L
R
Chimpanzee
Pan troglodytes
XP_516998
125
13542
Y114
G
G
L
N
K
K
A
Y
S
M
A
K
Y
L
R
Rhesus Macaque
Macaca mulatta
XP_001102817
303
32122
Y292
G
G
L
N
K
K
A
Y
S
M
A
K
Y
L
R
Dog
Lupus familis
XP_849132
168
17690
Y157
G
M
I
N
K
K
C
Y
E
M
A
S
H
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJV2
140
15014
Y129
G
G
L
N
K
K
A
Y
S
M
A
K
Y
L
R
Rat
Rattus norvegicus
Q9EPC6
140
14984
Y129
G
G
L
N
K
K
A
Y
S
M
A
K
Y
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507138
140
15036
Y129
G
G
L
N
K
K
A
Y
S
M
A
K
Y
L
R
Chicken
Gallus gallus
NP_001073228
140
15028
Y129
G
G
L
N
K
K
A
Y
S
M
A
K
Y
L
R
Frog
Xenopus laevis
NP_001080782
140
15141
Y129
G
G
L
N
K
K
T
Y
A
M
A
K
Y
L
R
Zebra Danio
Brachydanio rerio
NP_958874
139
14967
Y128
G
G
L
N
K
K
A
Y
S
M
A
K
Y
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P35083
131
14219
E120
G
Q
C
N
M
V
V
E
R
L
G
D
Y
L
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q42449
131
14248
E120
G
Q
C
N
L
V
V
E
R
L
G
D
Y
L
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.2
37.9
42.2
N.A.
99.2
96.4
N.A.
95.7
98.5
80
81.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
89.2
40.9
52.3
N.A.
100
97.8
N.A.
97.1
100
87.8
87.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
60
N.A.
100
100
N.A.
100
100
86.6
100
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
73.3
N.A.
100
100
N.A.
100
100
93.3
100
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
33.5
N.A.
34.2
N.A.
N.A.
Protein Similarity:
N.A.
45.7
N.A.
44.2
N.A.
N.A.
P-Site Identity:
N.A.
26.6
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
67
0
9
0
84
0
0
0
0
% A
% Cys:
0
0
17
0
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
17
9
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
100
75
0
0
0
0
0
0
0
0
17
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
9
% I
% Lys:
0
0
0
0
84
84
0
0
0
0
0
75
0
0
0
% K
% Leu:
0
0
75
0
9
0
0
0
0
17
0
0
0
100
0
% L
% Met:
0
9
0
0
9
0
0
0
0
84
0
0
0
0
0
% M
% Asn:
0
0
0
100
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
17
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
17
0
0
0
0
0
84
% R
% Ser:
0
0
0
0
0
0
0
0
67
0
0
9
0
0
0
% S
% Thr:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
17
17
0
0
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
84
0
0
0
0
92
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _