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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP6
All Species:
9.39
Human Site:
T1306
Identified Species:
22.96
UniProt:
P35125
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35125
NP_004496.2
1406
158658
T1306
T
D
D
Q
R
E
D
T
H
I
K
P
I
Y
N
Chimpanzee
Pan troglodytes
XP_511615
1601
181197
T1501
T
D
D
Q
R
E
D
T
R
I
K
P
I
Y
N
Rhesus Macaque
Macaca mulatta
XP_001112605
584
64806
C485
Y
K
D
D
S
V
E
C
L
T
T
K
F
G
Q
Dog
Lupus familis
XP_537710
1221
137606
H1122
D
D
Q
R
E
D
V
H
V
K
P
I
Y
N
L
Cat
Felis silvestris
Mouse
Mus musculus
Q80XC3
819
93555
E720
P
P
V
D
Y
L
P
E
N
R
K
W
S
E
V
Rat
Rattus norvegicus
NP_001100502
1431
161903
T1331
T
D
D
Q
R
E
D
T
H
S
K
P
I
Y
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510553
1599
180717
V1499
T
D
D
Q
R
E
D
V
C
I
K
P
I
Y
N
Chicken
Gallus gallus
XP_415892
1660
188103
V1560
A
D
D
Q
R
E
D
V
C
V
N
P
I
Y
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_686236
1675
189193
I1575
T
P
H
Q
R
N
D
I
C
L
E
S
L
Y
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZSB5
923
103680
S824
P
V
H
D
L
D
L
S
K
Y
V
K
N
K
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
60.4
29.5
64.8
N.A.
21.9
61.5
N.A.
55.2
52.7
N.A.
46.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
67.7
33.8
72.2
N.A.
35.1
70.3
N.A.
64.1
62.4
N.A.
58.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
6.6
6.6
N.A.
6.6
93.3
N.A.
86.6
66.6
N.A.
40
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
13.3
20
N.A.
13.3
93.3
N.A.
86.6
73.3
N.A.
60
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
30
0
0
0
0
0
0
% C
% Asp:
10
60
60
30
0
20
60
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
10
50
10
10
0
0
10
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% G
% His:
0
0
20
0
0
0
0
10
20
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
0
30
0
10
50
0
0
% I
% Lys:
0
10
0
0
0
0
0
0
10
10
50
20
0
10
0
% K
% Leu:
0
0
0
0
10
10
10
0
10
10
0
0
10
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
10
0
10
0
10
10
70
% N
% Pro:
20
20
0
0
0
0
10
0
0
0
10
50
0
0
0
% P
% Gln:
0
0
10
60
0
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
0
0
0
10
60
0
0
0
10
10
0
0
0
0
0
% R
% Ser:
0
0
0
0
10
0
0
10
0
10
0
10
10
0
0
% S
% Thr:
50
0
0
0
0
0
0
30
0
10
10
0
0
0
0
% T
% Val:
0
10
10
0
0
10
10
20
10
10
10
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% W
% Tyr:
10
0
0
0
10
0
0
0
0
10
0
0
10
60
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _