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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: USP6 All Species: 2.73
Human Site: T72 Identified Species: 6.67
UniProt: P35125 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P35125 NP_004496.2 1406 158658 T72 K K I R R E M T R T S K W M E
Chimpanzee Pan troglodytes XP_511615 1601 181197 G66 E V I Y C S F G G T S K G L H
Rhesus Macaque Macaca mulatta XP_001112605 584 64806
Dog Lupus familis XP_537710 1221 137606
Cat Felis silvestris
Mouse Mus musculus Q80XC3 819 93555
Rat Rattus norvegicus NP_001100502 1431 161903 E102 R T G R F D L E T F G P L V S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510553 1599 180717 L157 F T F S R W L L S G G V Y V T
Chicken Gallus gallus XP_415892 1660 188103 S88 F K R T C G L S Y Y M T Q Q C
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_686236 1675 189193 T133 S G L S V Y M T Q Q C F F R E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZSB5 923 103680
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 60.4 29.5 64.8 N.A. 21.9 61.5 N.A. 55.2 52.7 N.A. 46.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 67.7 33.8 72.2 N.A. 35.1 70.3 N.A. 64.1 62.4 N.A. 58.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 26.6 0 0 N.A. 0 6.6 N.A. 6.6 6.6 N.A. 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 40 0 0 N.A. 0 33.3 N.A. 26.6 20 N.A. 40 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 23.6 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 37.8 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 0 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 20 0 0 0 0 0 10 0 0 0 10 % C
% Asp: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % D
% Glu: 10 0 0 0 0 10 0 10 0 0 0 0 0 0 20 % E
% Phe: 20 0 10 0 10 0 10 0 0 10 0 10 10 0 0 % F
% Gly: 0 10 10 0 0 10 0 10 10 10 20 0 10 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % H
% Ile: 0 0 20 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 10 20 0 0 0 0 0 0 0 0 0 20 0 0 0 % K
% Leu: 0 0 10 0 0 0 30 10 0 0 0 0 10 10 0 % L
% Met: 0 0 0 0 0 0 20 0 0 0 10 0 0 10 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 10 10 0 0 10 10 0 % Q
% Arg: 10 0 10 20 20 0 0 0 10 0 0 0 0 10 0 % R
% Ser: 10 0 0 20 0 10 0 10 10 0 20 0 0 0 10 % S
% Thr: 0 20 0 10 0 0 0 20 10 20 0 10 0 0 10 % T
% Val: 0 10 0 0 10 0 0 0 0 0 0 10 0 20 0 % V
% Trp: 0 0 0 0 0 10 0 0 0 0 0 0 10 0 0 % W
% Tyr: 0 0 0 10 0 10 0 0 10 10 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _