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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GJA4
All Species:
26.67
Human Site:
S287
Identified Species:
65.19
UniProt:
P35212
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35212
NP_002051.2
333
37414
S287
T
Y
N
G
L
S
S
S
E
Q
N
W
A
N
L
Chimpanzee
Pan troglodytes
XP_001166035
333
37358
S287
T
Y
N
G
L
S
S
S
E
Q
N
W
A
N
L
Rhesus Macaque
Macaca mulatta
XP_001108253
333
37476
S287
T
Y
N
G
L
S
S
S
E
Q
N
W
A
N
L
Dog
Lupus familis
XP_539602
333
37317
S287
T
Y
N
G
L
S
S
S
E
Q
N
W
A
N
L
Cat
Felis silvestris
Mouse
Mus musculus
P28235
333
37578
T287
T
Y
N
G
L
S
S
T
E
Q
N
W
A
N
L
Rat
Rattus norvegicus
Q03190
333
37538
T287
T
Y
N
G
L
S
S
T
E
Q
N
W
A
N
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507730
337
38135
S295
T
Y
N
K
L
S
S
S
E
Q
N
W
A
N
F
Chicken
Gallus gallus
P14154
381
43107
E306
N
Y
N
K
Q
A
S
E
Q
N
W
A
N
Y
S
Frog
Xenopus laevis
P51914
352
40615
N293
Y
P
Q
Y
K
M
P
N
E
Q
N
W
V
N
F
Zebra Danio
Brachydanio rerio
O57474
381
43436
E306
N
Y
N
K
Q
A
N
E
Q
N
W
A
N
Y
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.5
95.1
N.A.
88.8
88.5
N.A.
71.8
43.8
59.6
44.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
99.4
98.1
N.A.
95.1
94.8
N.A.
81
60.6
73.8
61.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
86.6
20
33.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
86.6
33.3
40
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
20
0
0
0
0
0
20
70
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
20
80
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
20
% F
% Gly:
0
0
0
60
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
30
10
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
70
0
0
0
0
0
0
0
0
0
60
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
20
0
90
0
0
0
10
10
0
20
80
0
20
80
0
% N
% Pro:
0
10
0
0
0
0
10
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
0
20
0
0
0
20
80
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
70
80
50
0
0
0
0
0
0
20
% S
% Thr:
70
0
0
0
0
0
0
20
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
20
80
0
0
0
% W
% Tyr:
10
90
0
10
0
0
0
0
0
0
0
0
0
20
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _