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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTNNA1
All Species:
6.97
Human Site:
S268
Identified Species:
11.79
UniProt:
P35221
Number Species:
13
Phosphosite Substitution
Charge Score:
0.46
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35221
NP_001894.2
906
100071
S268
A
T
A
S
D
D
A
S
Q
H
Q
G
G
G
G
Chimpanzee
Pan troglodytes
XP_001172018
906
100083
S268
A
T
A
S
D
D
A
S
Q
H
Q
G
G
G
G
Rhesus Macaque
Macaca mulatta
XP_001112889
963
107071
E300
Q
A
T
S
P
T
D
E
A
K
G
H
T
G
I
Dog
Lupus familis
XP_540203
909
100744
E266
Q
A
T
S
P
T
D
E
A
K
G
H
T
G
I
Cat
Felis silvestris
Mouse
Mus musculus
P26231
906
100088
A268
A
T
A
S
D
D
A
A
Q
H
Q
G
G
S
G
Rat
Rattus norvegicus
NP_001007146
908
100218
Q270
A
S
D
D
A
S
Q
Q
Q
G
G
G
G
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516414
732
81211
E159
V
Q
L
K
I
V
E
E
G
I
L
K
L
R
N
Chicken
Gallus gallus
P30997
906
100673
E266
Q
A
T
S
P
T
D
E
N
K
G
H
T
G
I
Frog
Xenopus laevis
Q6GLP0
966
107082
E266
Q
A
T
S
P
T
D
E
K
Q
A
H
T
G
I
Zebra Danio
Brachydanio rerio
B7ZC77
865
95838
E226
Q
A
T
S
P
T
D
E
K
H
G
H
A
G
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P35220
917
102426
P271
A
Q
G
K
S
S
Q
P
T
D
I
Y
S
G
A
Honey Bee
Apis mellifera
XP_625229
909
101515
T264
Q
G
K
T
P
I
D
T
Q
H
P
Y
E
G
P
Nematode Worm
Caenorhab. elegans
P90947
927
103976
T262
N
G
Q
Q
P
K
V
T
F
S
E
Y
G
R
I
Sea Urchin
Strong. purpuratus
XP_784341
911
102424
A267
Q
A
T
G
D
S
S
A
N
P
N
I
E
G
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
76.9
81
N.A.
99.4
99.2
N.A.
76.9
81.6
76.1
79
N.A.
61.5
64.9
37.7
63.6
Protein Similarity:
100
99.8
85.6
90
N.A.
99.7
99.5
N.A.
78.9
90.5
84.7
87.9
N.A.
78.4
80.6
59.7
80.9
P-Site Identity:
100
100
13.3
13.3
N.A.
86.6
40
N.A.
0
13.3
13.3
20
N.A.
13.3
20
6.6
13.3
P-Site Similarity:
100
100
13.3
13.3
N.A.
93.3
46.6
N.A.
0
13.3
20
26.6
N.A.
13.3
33.3
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
36
43
22
0
8
0
22
15
15
0
8
0
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
8
29
22
43
0
0
8
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
8
43
0
0
8
0
15
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
15
8
8
0
0
0
0
8
8
36
29
36
79
29
% G
% His:
0
0
0
0
0
0
0
0
0
36
0
36
0
0
0
% H
% Ile:
0
0
0
0
8
8
0
0
0
8
8
8
0
0
43
% I
% Lys:
0
0
8
15
0
8
0
0
15
22
0
8
0
0
0
% K
% Leu:
0
0
8
0
0
0
0
0
0
0
8
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
15
0
8
0
0
0
8
% N
% Pro:
0
0
0
0
50
0
0
8
0
8
8
0
0
0
8
% P
% Gln:
50
15
8
8
0
0
15
8
36
8
22
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% R
% Ser:
0
8
0
58
8
22
8
15
0
8
0
0
8
8
8
% S
% Thr:
0
22
43
8
0
36
0
15
8
0
0
0
29
0
0
% T
% Val:
8
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
22
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _