KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTNNB1
All Species:
22.73
Human Site:
S29
Identified Species:
38.46
UniProt:
P35222
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35222
NP_001091679.1
781
85497
S29
V
S
H
W
Q
Q
Q
S
Y
L
D
S
G
I
H
Chimpanzee
Pan troglodytes
XP_001137676
774
84747
I28
Q
S
Y
L
D
S
G
I
H
S
G
A
T
T
T
Rhesus Macaque
Macaca mulatta
XP_001115474
511
55731
Dog
Lupus familis
XP_850439
744
81740
G25
Q
T
Y
T
Y
D
S
G
I
H
S
G
A
N
T
Cat
Felis silvestris
Mouse
Mus musculus
Q02248
781
85452
S29
V
S
H
W
Q
Q
Q
S
Y
L
D
S
G
I
H
Rat
Rattus norvegicus
Q9WU82
781
85436
S29
V
S
H
W
Q
Q
Q
S
Y
L
D
S
G
I
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516985
781
85506
S29
V
S
H
W
Q
Q
Q
S
Y
L
D
S
G
I
H
Chicken
Gallus gallus
NP_990412
781
85420
S29
V
S
H
W
Q
Q
Q
S
Y
L
D
S
G
I
H
Frog
Xenopus laevis
P26233
781
85431
S29
V
S
H
W
Q
Q
Q
S
Y
L
D
S
G
I
H
Zebra Danio
Brachydanio rerio
NP_571134
780
85502
Q28
A
V
S
H
W
Q
Q
Q
S
Y
L
D
S
G
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P18824
843
91134
Q37
E
Q
T
L
M
W
Q
Q
N
S
Y
L
G
D
S
Honey Bee
Apis mellifera
XP_391947
811
88602
Q38
E
Q
T
L
M
W
Q
Q
N
S
Y
L
G
D
S
Nematode Worm
Caenorhab. elegans
O44326
678
74493
I24
V
E
T
R
T
S
R
I
R
S
A
M
F
P
D
Sea Urchin
Strong. purpuratus
NP_001027543
825
89711
G50
H
G
Y
G
M
D
S
G
F
Q
S
N
A
T
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
65.4
66.4
N.A.
99.8
99.7
N.A.
99.7
99.3
97.4
97.1
N.A.
65.7
67.6
28.5
67.2
Protein Similarity:
100
99
65.4
77.4
N.A.
99.8
99.7
N.A.
99.8
99.6
99
98.9
N.A.
77.2
80.1
46.4
77.7
P-Site Identity:
100
6.6
0
0
N.A.
100
100
N.A.
100
100
100
13.3
N.A.
13.3
13.3
6.6
0
P-Site Similarity:
100
26.6
0
13.3
N.A.
100
100
N.A.
100
100
100
13.3
N.A.
13.3
13.3
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
0
0
8
8
15
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
15
0
0
0
0
43
8
0
15
8
% D
% Glu:
15
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% F
% Gly:
0
8
0
8
0
0
8
15
0
0
8
8
58
8
0
% G
% His:
8
0
43
8
0
0
0
0
8
8
0
0
0
0
43
% H
% Ile:
0
0
0
0
0
0
0
15
8
0
0
0
0
43
8
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
22
0
0
0
0
0
43
8
15
0
0
0
% L
% Met:
0
0
0
0
22
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
15
0
0
8
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
15
15
0
0
43
50
65
22
0
8
0
0
0
0
0
% Q
% Arg:
0
0
0
8
0
0
8
0
8
0
0
0
0
0
0
% R
% Ser:
0
50
8
0
0
15
15
43
8
29
15
43
8
0
22
% S
% Thr:
0
8
22
8
8
0
0
0
0
0
0
0
8
15
15
% T
% Val:
50
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
43
8
15
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
22
0
8
0
0
0
43
8
15
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _