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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SERPINB6
All Species:
7.27
Human Site:
S125
Identified Species:
20
UniProt:
P35237
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35237
NP_004559.4
376
42622
S125
M
E
E
L
D
F
I
S
A
V
E
K
S
R
K
Chimpanzee
Pan troglodytes
XP_512167
488
55435
E237
L
E
E
L
S
F
A
E
D
T
E
E
C
R
K
Rhesus Macaque
Macaca mulatta
XP_001093348
378
43183
N126
L
K
Q
L
D
F
L
N
D
T
E
K
S
R
T
Dog
Lupus familis
XP_848373
381
42676
Q129
D
F
L
S
A
C
E
Q
S
R
E
H
I
T
A
Cat
Felis silvestris
Mouse
Mus musculus
Q60854
378
42580
G127
L
E
E
L
D
F
Q
G
A
T
E
E
S
R
Q
Rat
Rattus norvegicus
Q4G075
379
42708
H123
L
A
P
V
D
F
Q
H
A
S
E
D
A
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505689
375
42423
Q123
L
E
H
V
N
F
A
Q
E
S
E
K
S
R
E
Chicken
Gallus gallus
O73790
410
47365
T151
P
Q
K
V
N
F
K
T
A
P
E
Q
S
R
K
Frog
Xenopus laevis
Q52L45
377
42679
S124
L
G
T
V
D
F
I
S
A
L
E
D
A
R
K
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.4
72.7
76.6
N.A.
76.7
49.8
N.A.
68
43.4
51.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
62.2
85.7
86.8
N.A.
87.3
68.8
N.A.
83.5
61.9
71.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
46.6
46.6
6.6
N.A.
60
40
N.A.
40
40
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
60
80
13.3
N.A.
80
60
N.A.
66.6
80
80
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
0
12
0
23
0
56
0
0
0
23
0
12
% A
% Cys:
0
0
0
0
0
12
0
0
0
0
0
0
12
0
0
% C
% Asp:
12
0
0
0
56
0
0
0
23
0
0
23
0
0
0
% D
% Glu:
0
45
34
0
0
0
12
12
12
0
100
23
0
0
12
% E
% Phe:
0
12
0
0
0
89
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
12
0
0
0
0
0
12
0
0
0
0
0
0
0
% G
% His:
0
0
12
0
0
0
0
12
0
0
0
12
0
0
0
% H
% Ile:
0
0
0
0
0
0
23
0
0
0
0
0
12
0
0
% I
% Lys:
0
12
12
0
0
0
12
0
0
0
0
34
0
0
56
% K
% Leu:
67
0
12
45
0
0
12
0
0
12
0
0
0
0
0
% L
% Met:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
23
0
0
12
0
0
0
0
0
0
0
% N
% Pro:
12
0
12
0
0
0
0
0
0
12
0
0
0
0
0
% P
% Gln:
0
12
12
0
0
0
23
23
0
0
0
12
0
0
12
% Q
% Arg:
0
0
0
0
0
0
0
0
0
12
0
0
0
89
0
% R
% Ser:
0
0
0
12
12
0
0
23
12
23
0
0
56
0
0
% S
% Thr:
0
0
12
0
0
0
0
12
0
34
0
0
0
12
12
% T
% Val:
0
0
0
45
0
0
0
0
0
12
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _