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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SERPINB6
All Species:
16.67
Human Site:
T249
Identified Species:
45.83
UniProt:
P35237
Number Species:
8
Phosphosite Substitution
Charge Score:
0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35237
NP_004559.4
376
42622
T249
R
T
V
E
K
E
L
T
Y
E
K
F
V
E
W
Chimpanzee
Pan troglodytes
XP_512167
488
55435
Y361
V
V
E
K
A
L
T
Y
E
K
F
K
A
W
T
Rhesus Macaque
Macaca mulatta
XP_001093348
378
43183
S250
K
M
V
E
K
K
L
S
Y
E
R
F
I
E
W
Dog
Lupus familis
XP_848373
381
42676
T253
E
T
V
E
T
E
L
T
Y
E
K
F
T
E
W
Cat
Felis silvestris
Mouse
Mus musculus
Q60854
378
42580
T251
S
T
V
E
K
E
V
T
Y
E
K
F
I
E
W
Rat
Rattus norvegicus
Q4G075
379
42708
E247
S
T
G
L
K
K
I
E
E
Q
I
T
L
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505689
375
42423
S247
S
T
V
E
K
E
L
S
Y
E
K
F
A
D
W
Chicken
Gallus gallus
O73790
410
47365
E275
T
T
G
L
E
Q
L
E
R
E
L
T
Y
E
R
Frog
Xenopus laevis
Q52L45
377
42679
E248
T
T
G
L
Q
Q
L
E
K
E
L
S
L
E
K
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.4
72.7
76.6
N.A.
76.7
49.8
N.A.
68
43.4
51.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
62.2
85.7
86.8
N.A.
87.3
68.8
N.A.
83.5
61.9
71.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
60
80
N.A.
80
20
N.A.
73.3
26.6
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
93.3
80
N.A.
93.3
46.6
N.A.
86.6
40
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
12
0
0
0
0
0
0
0
23
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% D
% Glu:
12
0
12
56
12
45
0
34
23
78
0
0
0
78
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
12
56
0
0
0
% F
% Gly:
0
0
34
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
12
0
0
0
12
0
23
0
0
% I
% Lys:
12
0
0
12
56
23
0
0
12
12
45
12
0
0
23
% K
% Leu:
0
0
0
34
0
12
67
0
0
0
23
0
23
0
0
% L
% Met:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
12
23
0
0
0
12
0
0
0
0
0
% Q
% Arg:
12
0
0
0
0
0
0
0
12
0
12
0
0
0
12
% R
% Ser:
34
0
0
0
0
0
0
23
0
0
0
12
0
0
0
% S
% Thr:
23
78
0
0
12
0
12
34
0
0
0
23
12
0
12
% T
% Val:
12
12
56
0
0
0
12
0
0
0
0
0
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
56
% W
% Tyr:
0
0
0
0
0
0
0
12
56
0
0
0
12
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _