KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NF2
All Species:
21.21
Human Site:
S566
Identified Species:
42.42
UniProt:
P35240
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35240
NP_000259.1
595
69690
S566
D
I
L
H
N
E
N
S
D
R
G
G
S
S
K
Chimpanzee
Pan troglodytes
XP_001136298
595
69538
S566
D
I
L
H
N
E
N
S
D
R
G
G
S
S
K
Rhesus Macaque
Macaca mulatta
XP_001106489
595
69702
S566
D
I
L
H
N
E
N
S
D
R
G
G
S
S
K
Dog
Lupus familis
XP_534729
596
69793
S566
D
I
L
H
N
E
N
S
D
R
G
G
T
S
S
Cat
Felis silvestris
Mouse
Mus musculus
P46662
596
69758
S566
D
V
L
H
S
E
S
S
D
R
G
G
P
S
S
Rat
Rattus norvegicus
Q63648
586
68693
K548
E
I
E
A
L
K
L
K
E
R
E
T
A
L
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521866
636
73533
P556
F
P
P
W
D
G
A
P
G
P
P
G
H
A
L
Chicken
Gallus gallus
Q9PU45
583
68536
V555
D
V
L
H
A
E
N
V
K
A
G
R
G
K
Y
Frog
Xenopus laevis
NP_001086957
585
68810
K556
E
I
E
S
L
K
L
K
E
R
E
S
A
M
D
Zebra Danio
Brachydanio rerio
NP_001122179
593
69546
T565
D
I
L
H
N
E
N
T
E
K
G
T
S
K
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24564
635
74474
I607
D
I
L
S
E
A
Q
I
K
A
G
E
N
K
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781142
608
70697
N580
D
R
I
Y
N
E
V
N
S
R
G
E
N
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.4
99.8
99.5
N.A.
98.3
95.1
N.A.
61.7
44.8
86.8
82.5
N.A.
47.4
N.A.
N.A.
56.5
Protein Similarity:
100
97.6
99.8
99.5
N.A.
99.3
96.6
N.A.
76.5
65.5
92.7
91.2
N.A.
66.3
N.A.
N.A.
75.4
P-Site Identity:
100
100
100
86.6
N.A.
66.6
13.3
N.A.
6.6
40
13.3
60
N.A.
26.6
N.A.
N.A.
40
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
40
N.A.
20
46.6
40
86.6
N.A.
33.3
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
9
9
9
0
0
17
0
0
17
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
75
0
0
0
9
0
0
0
42
0
0
0
0
0
17
% D
% Glu:
17
0
17
0
9
67
0
0
25
0
17
17
0
0
0
% E
% Phe:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
9
0
0
9
0
75
50
9
0
0
% G
% His:
0
0
0
59
0
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
0
67
9
0
0
0
0
9
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
17
0
17
17
9
0
0
0
34
34
% K
% Leu:
0
0
67
0
17
0
17
0
0
0
0
0
0
9
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
0
0
0
0
50
0
50
9
0
0
0
0
17
0
0
% N
% Pro:
0
9
9
0
0
0
0
9
0
9
9
0
9
0
0
% P
% Gln:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
9
% Q
% Arg:
0
9
0
0
0
0
0
0
0
67
0
9
0
0
0
% R
% Ser:
0
0
0
17
9
0
9
42
9
0
0
9
34
42
17
% S
% Thr:
0
0
0
0
0
0
0
9
0
0
0
17
9
0
0
% T
% Val:
0
17
0
0
0
0
9
9
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
17
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _