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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NF2
All Species:
10.91
Human Site:
T581
Identified Species:
21.82
UniProt:
P35240
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35240
NP_000259.1
595
69690
T581
H
N
T
I
K
K
L
T
L
Q
S
A
K
S
R
Chimpanzee
Pan troglodytes
XP_001136298
595
69538
T581
H
N
T
I
K
K
L
T
L
Q
S
A
K
S
R
Rhesus Macaque
Macaca mulatta
XP_001106489
595
69702
T581
H
N
T
I
K
K
L
T
L
Q
S
T
K
S
R
Dog
Lupus familis
XP_534729
596
69793
L581
K
H
N
T
I
K
K
L
T
L
Q
S
A
K
S
Cat
Felis silvestris
Mouse
Mus musculus
P46662
596
69758
L581
K
H
N
T
I
K
K
L
T
L
Q
S
A
K
S
Rat
Rattus norvegicus
Q63648
586
68693
D563
I
L
H
S
E
H
S
D
S
G
T
S
S
K
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521866
636
73533
G571
G
K
E
R
R
D
G
G
P
K
K
H
H
Q
G
Chicken
Gallus gallus
Q9PU45
583
68536
Q570
K
T
L
R
Q
I
R
Q
G
N
T
K
Q
R
I
Frog
Xenopus laevis
NP_001086957
585
68810
S571
I
M
H
E
N
A
G
S
K
Q
N
T
I
K
K
Zebra Danio
Brachydanio rerio
NP_001122179
593
69546
L580
S
N
F
K
K
L
T
L
Q
S
T
K
S
R
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24564
635
74474
S622
S
T
L
K
K
L
K
S
G
S
T
K
A
R
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781142
608
70697
Q595
T
T
L
N
K
I
T
Q
G
S
T
R
A
R
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.4
99.8
99.5
N.A.
98.3
95.1
N.A.
61.7
44.8
86.8
82.5
N.A.
47.4
N.A.
N.A.
56.5
Protein Similarity:
100
97.6
99.8
99.5
N.A.
99.3
96.6
N.A.
76.5
65.5
92.7
91.2
N.A.
66.3
N.A.
N.A.
75.4
P-Site Identity:
100
100
93.3
6.6
N.A.
6.6
0
N.A.
0
0
6.6
13.3
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
100
93.3
20
N.A.
20
20
N.A.
13.3
20
26.6
20
N.A.
20
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
0
0
0
0
0
17
34
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
9
0
9
0
0
0
0
0
0
0
% D
% Glu:
0
0
9
9
9
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
0
0
0
0
17
9
25
9
0
0
0
0
9
% G
% His:
25
17
17
0
0
9
0
0
0
0
0
9
9
0
9
% H
% Ile:
17
0
0
25
17
17
0
0
0
0
0
0
9
0
9
% I
% Lys:
25
9
0
17
50
42
25
0
9
9
9
25
25
34
9
% K
% Leu:
0
9
25
0
0
17
25
25
25
17
0
0
0
0
0
% L
% Met:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
34
17
9
9
0
0
0
0
9
9
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
9
0
0
17
9
34
17
0
9
9
0
% Q
% Arg:
0
0
0
17
9
0
9
0
0
0
0
9
0
34
25
% R
% Ser:
17
0
0
9
0
0
9
17
9
25
25
25
17
25
17
% S
% Thr:
9
25
25
17
0
0
17
25
17
0
42
17
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
25
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _