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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RDX
All Species:
22.73
Human Site:
S501
Identified Species:
55.56
UniProt:
P35241
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35241
NP_002897.1
583
68564
S501
A
E
A
S
A
E
L
S
N
E
G
V
M
N
H
Chimpanzee
Pan troglodytes
XP_522176
765
86955
S683
A
E
A
S
A
E
L
S
N
E
G
V
M
N
H
Rhesus Macaque
Macaca mulatta
XP_001104955
604
71016
S501
A
E
A
S
A
E
L
S
N
E
G
V
M
N
H
Dog
Lupus familis
XP_536581
583
68531
S501
A
E
A
S
A
E
L
S
N
D
G
V
M
N
H
Cat
Felis silvestris
Mouse
Mus musculus
P26043
583
68582
S501
A
E
A
S
A
E
L
S
S
E
G
V
M
N
H
Rat
Rattus norvegicus
O35763
577
67720
R495
A
E
A
S
A
E
L
R
A
D
A
M
A
K
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9PU45
583
68536
S501
A
E
A
S
A
E
L
S
S
D
G
V
M
N
H
Frog
Xenopus laevis
NP_001090034
580
68116
K498
A
E
A
S
A
E
L
K
S
E
A
M
I
K
D
Zebra Danio
Brachydanio rerio
O57457
619
70690
P536
H
R
S
R
S
R
S
P
D
V
Q
A
K
E
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P46150
578
68123
L496
G
G
D
V
S
R
D
L
D
T
D
E
H
I
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.2
96.3
99.3
N.A.
98.2
80.6
N.A.
N.A.
97.7
81.4
21.9
N.A.
58.8
N.A.
N.A.
N.A.
Protein Similarity:
100
76.2
96.5
100
N.A.
99.6
89.5
N.A.
N.A.
99.6
90.3
42.4
N.A.
75.3
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
93.3
46.6
N.A.
N.A.
86.6
53.3
0
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
60
N.A.
N.A.
100
73.3
20
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
80
0
80
0
80
0
0
0
10
0
20
10
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
10
0
20
30
10
0
0
0
20
% D
% Glu:
0
80
0
0
0
80
0
0
0
50
0
10
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
10
0
0
0
0
0
0
0
0
60
0
0
0
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
10
0
60
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% I
% Lys:
0
0
0
0
0
0
0
10
0
0
0
0
10
20
10
% K
% Leu:
0
0
0
0
0
0
80
10
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
20
60
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
40
0
0
0
0
60
0
% N
% Pro:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% Q
% Arg:
0
10
0
10
0
20
0
10
0
0
0
0
0
0
0
% R
% Ser:
0
0
10
80
20
0
10
60
30
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% T
% Val:
0
0
0
10
0
0
0
0
0
10
0
60
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _