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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RCVRN All Species: 20.61
Human Site: T147 Identified Species: 34.87
UniProt: P35243 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P35243 NP_002894.1 200 23130 T147 L L P D D E N T P E K R A E K
Chimpanzee Pan troglodytes XP_001155509 344 38260 P296 M P E D E S T P E K R T E K I
Rhesus Macaque Macaca mulatta XP_001113548 200 23051 T147 L L P E D E N T P E K R A E K
Dog Lupus familis XP_852217 329 37131 P281 M P E D E S T P E K R T D K I
Cat Felis silvestris
Mouse Mus musculus P34057 202 23388 T147 L L P D D E N T P E K R A E K
Rat Rattus norvegicus P62749 193 22320 T149 E S T P E K R T D K I F R Q M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514627 193 22313 T147 G L P E D E N T P Q K R A D K
Chicken Gallus gallus P22728 192 22503 S147 Q L P E D E N S P Q K R A D K
Frog Xenopus laevis Q6DCM9 193 22267 T149 E S T P E K R T D K I F K Q M
Zebra Danio Brachydanio rerio A9JTH1 193 22206 E150 S T P E K R T E K I F R Q M D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P42325 190 21875 D150 S T P E K R T D K I F R Q M D
Honey Bee Apis mellifera XP_392256 192 21952 D150 S T P E K R T D K I F R Q M D
Nematode Worm Caenorhab. elegans P36609 190 21967 K148 S A D D S P R K R A K M I F E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q06389 190 21992 K150 A T P E M R V K K I F K L M D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 31.1 97.5 32.2 N.A. 87.1 48.5 N.A. 63.5 59 50 47 N.A. 48 48.5 43.5 N.A.
Protein Similarity: 100 43.5 99.5 46.5 N.A. 94.5 73.5 N.A. 79 80.5 73.5 71.5 N.A. 72.5 71.5 68 N.A.
P-Site Identity: 100 6.6 93.3 6.6 N.A. 100 6.6 N.A. 73.3 66.6 6.6 13.3 N.A. 13.3 13.3 13.3 N.A.
P-Site Similarity: 100 40 100 40 N.A. 100 33.3 N.A. 93.3 93.3 33.3 20 N.A. 20 20 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 36.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 59.5 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 0 0 0 0 0 0 8 0 0 36 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 36 36 0 0 15 15 0 0 0 8 15 29 % D
% Glu: 15 0 15 50 29 36 0 8 15 22 0 0 8 22 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 29 15 0 8 0 % F
% Gly: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 29 15 0 8 0 15 % I
% Lys: 0 0 0 0 22 15 0 15 29 29 43 8 8 15 36 % K
% Leu: 22 36 0 0 0 0 0 0 0 0 0 0 8 0 0 % L
% Met: 15 0 0 0 8 0 0 0 0 0 0 8 0 29 15 % M
% Asn: 0 0 0 0 0 0 36 0 0 0 0 0 0 0 0 % N
% Pro: 0 15 65 15 0 8 0 15 36 0 0 0 0 0 0 % P
% Gln: 8 0 0 0 0 0 0 0 0 15 0 0 22 15 0 % Q
% Arg: 0 0 0 0 0 29 22 0 8 0 15 58 8 0 0 % R
% Ser: 29 15 0 0 8 15 0 8 0 0 0 0 0 0 0 % S
% Thr: 0 29 15 0 0 0 36 43 0 0 0 15 0 0 0 % T
% Val: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _