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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RCVRN All Species: 15.76
Human Site: T45 Identified Species: 26.67
UniProt: P35243 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.31
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P35243 NP_002894.1 200 23130 T45 D C P T G R I T Q Q Q F Q S I
Chimpanzee Pan troglodytes XP_001155509 344 38260 N195 D C P T G I L N V D E F K K I
Rhesus Macaque Macaca mulatta XP_001113548 200 23051 T45 D C P S G R I T Q Q Q F Q S I
Dog Lupus familis XP_852217 329 37131 T180 D C P T G H L T V D E F K K I
Cat Felis silvestris
Mouse Mus musculus P34057 202 23388 T45 E C P S G R I T R Q E F E S I
Rat Rattus norvegicus P62749 193 22320 E47 T G H L T V D E F K K I Y A N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514627 193 22313 G45 Q C P D G R I G R V D F E R I
Chicken Gallus gallus P22728 192 22503 R45 Q C P D G R I R C D E F E R I
Frog Xenopus laevis Q6DCM9 193 22267 E47 T G H L T V E E F K K I Y A N
Zebra Danio Brachydanio rerio A9JTH1 193 22206 E47 S G N L S M E E F K K I Y G N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P42325 190 21875 E47 S G H L S V E E F K K I Y G N
Honey Bee Apis mellifera XP_392256 192 21952 F48 G H L S V E E F K K I Y G N F
Nematode Worm Caenorhab. elegans P36609 190 21967 T46 D C P K G H L T K E Q F I K V
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q06389 190 21992 D47 S G Q L A R E D F V K I Y K Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 31.1 97.5 32.2 N.A. 87.1 48.5 N.A. 63.5 59 50 47 N.A. 48 48.5 43.5 N.A.
Protein Similarity: 100 43.5 99.5 46.5 N.A. 94.5 73.5 N.A. 79 80.5 73.5 71.5 N.A. 72.5 71.5 68 N.A.
P-Site Identity: 100 46.6 93.3 53.3 N.A. 66.6 0 N.A. 46.6 46.6 0 0 N.A. 0 0 46.6 N.A.
P-Site Similarity: 100 66.6 100 73.3 N.A. 100 20 N.A. 60 60 20 13.3 N.A. 13.3 33.3 73.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 36.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 59.5 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 0 0 0 0 0 0 0 0 15 0 % A
% Cys: 0 58 0 0 0 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 36 0 0 15 0 0 8 8 0 22 8 0 0 0 0 % D
% Glu: 8 0 0 0 0 8 36 29 0 8 29 0 22 0 0 % E
% Phe: 0 0 0 0 0 0 0 8 36 0 0 58 0 0 8 % F
% Gly: 8 36 0 0 58 0 0 8 0 0 0 0 8 15 0 % G
% His: 0 8 22 0 0 15 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 8 36 0 0 0 8 36 8 0 50 % I
% Lys: 0 0 0 8 0 0 0 0 15 36 36 0 15 29 0 % K
% Leu: 0 0 8 36 0 0 22 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 0 0 0 8 0 0 0 0 0 8 29 % N
% Pro: 0 0 58 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 15 0 8 0 0 0 0 0 15 22 22 0 15 0 8 % Q
% Arg: 0 0 0 0 0 43 0 8 15 0 0 0 0 15 0 % R
% Ser: 22 0 0 22 15 0 0 0 0 0 0 0 0 22 0 % S
% Thr: 15 0 0 22 15 0 0 36 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 8 22 0 0 15 15 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 8 36 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _