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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RFC1 All Species: 12.73
Human Site: S329 Identified Species: 25.45
UniProt: P35251 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P35251 NP_002904.3 1148 128255 S329 M K R K E E S S Y K E I E P V
Chimpanzee Pan troglodytes XP_001140765 1148 128250 S329 M K R K E E S S Y K E I E P V
Rhesus Macaque Macaca mulatta XP_001091287 1148 128475 A329 M K R K E E S A Y K E T E S V
Dog Lupus familis XP_536259 1145 128125 S326 L L K K K G E S S Y K E T E P
Cat Felis silvestris
Mouse Mus musculus P35601 1131 125967 S326 M K A K E E S S Y N E T E L L
Rat Rattus norvegicus NP_445999 1131 125770 N324 L M K A Q E E N S Y K E T E L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512744 1233 136122 E412 A L L K Q K G E S E K E K G A
Chicken Gallus gallus NP_001006456 1147 128454 T326 L K Q K E E T T K R E S G T Q
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P35600 986 108596 I229 L N P G S K E I P K G S P D C
Honey Bee Apis mellifera XP_397246 911 103001 D154 I D S H E N N D E N K E K I S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797949 906 99249 E149 E M E E H D D E D F Q A T L R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38630 861 94885 I104 S S D S A S N I T A Q D V L D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 97.3 89.3 N.A. 82.4 81.3 N.A. 67.4 68.9 N.A. N.A. N.A. 39.9 36.2 N.A. 38
Protein Similarity: 100 99.6 98.5 93.7 N.A. 89.5 88.5 N.A. 77.2 79.6 N.A. N.A. N.A. 55.9 53.6 N.A. 52.2
P-Site Identity: 100 100 80 13.3 N.A. 66.6 6.6 N.A. 6.6 33.3 N.A. N.A. N.A. 6.6 6.6 N.A. 0
P-Site Similarity: 100 100 86.6 40 N.A. 73.3 46.6 N.A. 40 66.6 N.A. N.A. N.A. 20 33.3 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 30 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 46.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 9 9 9 0 0 9 0 9 0 9 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % C
% Asp: 0 9 9 0 0 9 9 9 9 0 0 9 0 9 9 % D
% Glu: 9 0 9 9 50 50 25 17 9 9 42 34 34 17 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % F
% Gly: 0 0 0 9 0 9 9 0 0 0 9 0 9 9 0 % G
% His: 0 0 0 9 9 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 0 0 0 0 0 0 17 0 0 0 17 0 9 0 % I
% Lys: 0 42 17 59 9 17 0 0 9 34 34 0 17 0 0 % K
% Leu: 34 17 9 0 0 0 0 0 0 0 0 0 0 25 17 % L
% Met: 34 17 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 9 0 0 0 9 17 9 0 17 0 0 0 0 0 % N
% Pro: 0 0 9 0 0 0 0 0 9 0 0 0 9 17 9 % P
% Gln: 0 0 9 0 17 0 0 0 0 0 17 0 0 0 9 % Q
% Arg: 0 0 25 0 0 0 0 0 0 9 0 0 0 0 9 % R
% Ser: 9 9 9 9 9 9 34 34 25 0 0 17 0 9 9 % S
% Thr: 0 0 0 0 0 0 9 9 9 0 0 17 25 9 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 25 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 34 17 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _