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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GTF2F1
All Species:
26.97
Human Site:
S279
Identified Species:
53.94
UniProt:
P35269
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35269
NP_002087.2
517
58240
S279
D
Y
M
S
D
G
S
S
S
S
Q
E
E
P
E
Chimpanzee
Pan troglodytes
XP_512314
517
58179
S279
D
Y
M
S
D
G
S
S
S
S
Q
E
E
P
E
Rhesus Macaque
Macaca mulatta
XP_001087325
517
58149
S279
D
Y
M
S
D
G
S
S
S
S
Q
D
E
P
E
Dog
Lupus familis
XP_533935
617
68750
S380
D
Y
M
S
D
G
S
S
S
S
Q
E
E
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q3THK3
508
57228
S279
D
Y
M
S
D
G
S
S
S
S
P
D
E
T
E
Rat
Rattus norvegicus
Q6AY96
508
57163
S279
D
Y
M
S
D
G
S
S
S
S
P
D
E
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q04870
524
58680
S285
D
Y
M
S
D
E
S
S
S
D
E
E
L
P
G
Zebra Danio
Brachydanio rerio
NP_956023
443
48920
D224
R
I
H
D
L
E
E
D
L
E
M
S
S
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q05913
577
64448
E314
D
Y
D
T
S
S
S
E
D
E
P
D
P
E
A
Honey Bee
Apis mellifera
XP_001122801
449
51831
D230
W
M
D
S
D
D
D
D
S
L
S
D
D
N
E
Nematode Worm
Caenorhab. elegans
NP_494756
481
54445
V261
R
V
E
D
K
D
D
V
A
K
Y
E
S
S
D
Sea Urchin
Strong. purpuratus
XP_001189317
490
55825
S251
D
Y
I
S
E
Q
S
S
D
D
D
E
M
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.4
78.2
N.A.
91.3
91.6
N.A.
N.A.
N.A.
75.7
60.1
N.A.
37
39.8
32.1
37.7
Protein Similarity:
100
99.8
99.2
80.8
N.A.
93.6
93.8
N.A.
N.A.
N.A.
88.7
70.7
N.A.
57.1
58
51.2
57.6
P-Site Identity:
100
100
93.3
93.3
N.A.
80
80
N.A.
N.A.
N.A.
66.6
6.6
N.A.
20
26.6
6.6
40
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
N.A.
N.A.
73.3
6.6
N.A.
33.3
40
20
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
9
0
0
0
0
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
75
0
17
17
67
17
17
17
17
17
9
42
9
9
9
% D
% Glu:
0
0
9
0
9
17
9
9
0
17
9
50
50
17
67
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
50
0
0
0
0
0
0
0
0
9
% G
% His:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
9
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
9
0
0
0
0
9
0
0
0
0
0
% K
% Leu:
0
0
0
0
9
0
0
0
9
9
0
0
9
9
9
% L
% Met:
0
9
59
0
0
0
0
0
0
0
9
0
9
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
25
0
9
34
0
% P
% Gln:
0
0
0
0
0
9
0
0
0
0
34
0
0
0
0
% Q
% Arg:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
75
9
9
75
67
67
50
9
9
17
9
0
% S
% Thr:
0
0
0
9
0
0
0
0
0
0
0
0
0
9
0
% T
% Val:
0
9
0
0
0
0
0
9
0
0
0
0
0
0
0
% V
% Trp:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
75
0
0
0
0
0
0
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _