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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GTF2F1
All Species:
20.3
Human Site:
S449
Identified Species:
40.61
UniProt:
P35269
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35269
NP_002087.2
517
58240
S449
S
G
K
T
T
P
N
S
G
D
V
Q
V
T
E
Chimpanzee
Pan troglodytes
XP_512314
517
58179
S449
S
G
K
T
T
P
S
S
G
D
V
Q
V
T
E
Rhesus Macaque
Macaca mulatta
XP_001087325
517
58149
S449
S
G
K
S
T
P
S
S
G
D
V
Q
V
T
E
Dog
Lupus familis
XP_533935
617
68750
S549
S
G
K
S
T
P
S
S
G
D
V
Q
V
T
E
Cat
Felis silvestris
Mouse
Mus musculus
Q3THK3
508
57228
A449
D
V
Q
V
T
E
D
A
V
R
R
Y
L
T
R
Rat
Rattus norvegicus
Q6AY96
508
57163
A449
D
V
Q
V
T
E
D
A
V
R
R
Y
L
T
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q04870
524
58680
S456
S
G
K
S
T
P
S
S
G
D
I
Q
L
T
E
Zebra Danio
Brachydanio rerio
NP_956023
443
48920
R386
L
L
T
E
D
A
V
R
R
Y
L
I
R
K
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q05913
577
64448
V510
T
S
F
S
G
G
K
V
E
D
Y
G
I
T
E
Honey Bee
Apis mellifera
XP_001122801
449
51831
L392
E
D
A
V
R
R
Y
L
M
R
K
P
M
T
T
Nematode Worm
Caenorhab. elegans
NP_494756
481
54445
K423
V
R
R
Y
L
R
R
K
P
H
T
T
K
E
L
Sea Urchin
Strong. purpuratus
XP_001189317
490
55825
S419
S
S
S
N
K
T
P
S
G
H
V
P
L
T
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.4
78.2
N.A.
91.3
91.6
N.A.
N.A.
N.A.
75.7
60.1
N.A.
37
39.8
32.1
37.7
Protein Similarity:
100
99.8
99.2
80.8
N.A.
93.6
93.8
N.A.
N.A.
N.A.
88.7
70.7
N.A.
57.1
58
51.2
57.6
P-Site Identity:
100
93.3
86.6
86.6
N.A.
13.3
13.3
N.A.
N.A.
N.A.
73.3
0
N.A.
20
6.6
0
40
P-Site Similarity:
100
100
100
100
N.A.
40
40
N.A.
N.A.
N.A.
100
6.6
N.A.
40
13.3
6.6
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
9
0
17
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
17
9
0
0
9
0
17
0
0
50
0
0
0
0
0
% D
% Glu:
9
0
0
9
0
17
0
0
9
0
0
0
0
9
59
% E
% Phe:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
42
0
0
9
9
0
0
50
0
0
9
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
17
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
9
9
9
0
0
% I
% Lys:
0
0
42
0
9
0
9
9
0
0
9
0
9
9
0
% K
% Leu:
9
9
0
0
9
0
0
9
0
0
9
0
34
0
9
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
9
0
0
% M
% Asn:
0
0
0
9
0
0
9
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
42
9
0
9
0
0
17
0
0
9
% P
% Gln:
0
0
17
0
0
0
0
0
0
0
0
42
0
0
0
% Q
% Arg:
0
9
9
0
9
17
9
9
9
25
17
0
9
0
17
% R
% Ser:
50
17
9
34
0
0
34
50
0
0
0
0
0
0
0
% S
% Thr:
9
0
9
17
59
9
0
0
0
0
9
9
0
84
9
% T
% Val:
9
17
0
25
0
0
9
9
17
0
42
0
34
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
9
0
0
9
9
17
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _