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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPR
All Species:
15.45
Human Site:
T22
Identified Species:
26.15
UniProt:
P35270
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35270
NP_003115.1
261
28048
T22
A
S
R
G
F
G
R
T
L
A
P
L
L
A
S
Chimpanzee
Pan troglodytes
XP_525784
261
27897
T22
A
S
R
G
F
G
R
T
L
A
P
L
L
A
S
Rhesus Macaque
Macaca mulatta
XP_001103332
261
28016
T22
A
S
R
G
F
G
R
T
L
A
P
L
L
A
S
Dog
Lupus familis
XP_540234
267
28592
A28
A
S
R
G
F
G
R
A
L
A
R
L
L
A
R
Cat
Felis silvestris
Mouse
Mus musculus
Q64105
261
27865
A23
A
S
R
G
F
G
R
A
L
A
P
Q
L
A
R
Rat
Rattus norvegicus
P18297
262
28110
A23
A
S
R
G
F
G
R
A
L
A
P
Q
L
A
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520473
236
25629
P16
R
G
A
R
P
A
A
P
A
E
G
M
E
G
A
Chicken
Gallus gallus
Q8JIS3
246
26149
A24
A
G
K
G
I
G
R
A
V
A
V
A
L
C
K
Frog
Xenopus laevis
Q7ZY31
263
28687
T26
A
S
R
G
F
G
R
T
L
A
H
E
L
C
P
Zebra Danio
Brachydanio rerio
NP_001019601
261
28523
A24
A
S
R
G
F
G
R
A
L
A
L
S
V
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624245
354
39811
Q115
A
S
R
G
I
G
R
Q
L
A
I
S
F
G
S
Nematode Worm
Caenorhab. elegans
Q21929
251
27201
E24
A
S
Q
G
I
G
K
E
I
C
L
S
L
A
K
Sea Urchin
Strong. purpuratus
XP_783056
275
30198
A25
G
S
R
G
I
G
R
A
I
A
V
T
L
S
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40579
254
27462
S17
V
S
R
G
I
G
K
S
I
V
D
V
L
F
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.5
96.9
80.9
N.A.
74.3
74.4
N.A.
46.3
26.4
55.5
52.4
N.A.
N.A.
25.4
26
39.6
Protein Similarity:
100
98
99.6
89.1
N.A.
86.5
88.1
N.A.
58.6
44.8
69.9
74.3
N.A.
N.A.
41.5
46.3
58.5
P-Site Identity:
100
100
100
80
N.A.
80
80
N.A.
0
40
73.3
66.6
N.A.
N.A.
60
40
46.6
P-Site Similarity:
100
100
100
80
N.A.
80
80
N.A.
13.3
53.3
73.3
80
N.A.
N.A.
60
60
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
28.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
79
0
8
0
0
8
8
43
8
79
0
8
0
58
22
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
15
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
8
0
8
0
8
8
0
0
% E
% Phe:
0
0
0
0
58
0
0
0
0
0
0
0
8
8
0
% F
% Gly:
8
15
0
93
0
93
0
0
0
0
8
0
0
15
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
0
36
0
0
0
22
0
8
0
0
0
0
% I
% Lys:
0
0
8
0
0
0
15
0
0
0
0
0
0
0
15
% K
% Leu:
0
0
0
0
0
0
0
0
65
0
15
29
79
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
8
0
0
8
0
0
36
0
0
0
8
% P
% Gln:
0
0
8
0
0
0
0
8
0
0
0
15
0
0
0
% Q
% Arg:
8
0
79
8
0
0
79
0
0
0
8
0
0
0
15
% R
% Ser:
0
86
0
0
0
0
0
8
0
0
0
22
0
8
36
% S
% Thr:
0
0
0
0
0
0
0
29
0
0
0
8
0
0
0
% T
% Val:
8
0
0
0
0
0
0
0
8
8
15
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _